重组Anti-GPCR GPR37抗体[S02-9I6] (ab317386)
![Western blot - Anti-GPCR GPR37 Antibody [S02-9I6] (ab317386)](https://www.abcam.cn/ps/products/317/ab317386/Images/ab317386-536483-anti-gpcr-gpr37-antibody-s02-9i6-western-blot-brain-rat.jpg "Western blot - Anti-GPCR GPR37 Antibody [S02-9I6] (ab317386)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [S02-9I6] to GPCR GPR37
- Suitable for: WB
- Reacts with: Rat
概述
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产品名称
Anti-GPCR GPR37抗体[S02-9I6]
参阅全部 GPCR GPR37 一抗 -
描述
兔单克隆抗体[S02-9I6] to GPCR GPR37 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Rat
预测可用于: Human
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免疫原
Synthetic peptide corresponding to Human GPCR GPR37.
Database link: O15354 -
阳性对照
- WB: Rat brain lysate.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.4
Preservative: 0.01% Sodium azide
Constituents: 55.08% Water, 40% Glycerol (glycerin, glycerine), 0.98% Tris glycine, 0.88% Sodium chloride, 0.05% BSA -
Concentration information loading... -
纯度
Affinity purified -
克隆
单克隆 -
克隆编号
S02-9I6 -
同种型
IgG -
研究领域
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab317386于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000. Predicted molecular weight: 67 kDa.
|
| 说明 |
|---|
|
WB
1/1000. Predicted molecular weight: 67 kDa. |
靶标
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功能
Orphan receptor. May have a unique functional role in the central nervous system. -
组织特异性
Expressed in brain and spinal cord, and at lower levels in testis, placenta and liver, but no detectable expression observed in any other tissue. When overexpressed in cells, tends to become insoluble and unfolded. Accumulation of the unfolded protein may lead to dopaminergic neuronal death in juvenile Parkinson disease (PDJ). -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
翻译后修饰
Ubiquitinated by PARK2 in the presence of UBE2E1 and UBE2L3 in the endoplasmic reticulum. The unfolded form is specifically ubiquitinated by SYVN1, which promotes its proteasomal degradation and prevents neuronal cell death. -
细胞定位
Cell membrane. Endoplasmic reticulum membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 2861 Human
- Entrez Gene: 117549 Rat
- Omim: 602583 Human
- SwissProt: O15354 Human
- SwissProt: Q9QYC6 Rat
- Unigene: 731392 Human
- Unigene: 28035 Rat
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别名
- EDNRBL antibody
- Endothelin B receptor like protein 1 antibody
- Endothelin B receptor-like protein 1 antibody
see all
图片
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Western blot - Anti-GPCR GPR37 Antibody [S02-9I6] (ab317386)Anti-GPCR GPR37 Antibody [S02-9I6] (ab317386) at 1/1000 dilution + rat brain lysate
Predicted band size: 67 kDa
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab317386 尚未被引用在任何文献中。