重组Anti-GPCR GPR18抗体[EPR12359] (ab174835)
![Western blot - Anti-GPCR GPR18 antibody [EPR12359] (ab174835)](https://www.abcam.cn/ps/products/174/ab174835/Images/ab174835-200329-anti-gpcr-gpr18-antibody-epr12359-western-blot.jpg "Western blot - Anti-GPCR GPR18 antibody [EPR12359] (ab174835)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR12359] to GPCR GPR18
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
概述
-
产品名称
Anti-GPCR GPR18抗体[EPR12359]
参阅全部 GPCR GPR18 一抗 -
描述
兔单克隆抗体[EPR12359] to GPCR GPR18 -
宿主
Rabbit -
经测试应用
适用于: WBmore details
不适用于: Flow Cyt,ICC/IF,IHC-P or IP -
种属反应性
与反应: Human
预测可用于: Mouse, Rat
-
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
-
阳性对照
- HuT-78 and 293T cell lysates.
-
常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading... -
纯度
Tissue culture supernatant -
克隆
单克隆 -
克隆编号
EPR12359 -
同种型
IgG -
研究领域
相关产品
-
Alternative Versions
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab174835于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000 - 1/5000. Predicted molecular weight: 38 kDa.
|
| 说明 |
|---|
|
WB
1/1000 - 1/5000. Predicted molecular weight: 38 kDa. |
应用说明
Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
靶标
-
功能
Receptor for N-arachidonyl glycine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system. -
组织特异性
Most abundant in testis and spleen. Highly expressed in CD4 and CD8-positive T-cells as well as CD19-positive B-cells. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
细胞定位
Cell membrane. - Information by UniProt
-
数据库链接
- Entrez Gene: 2841 Human
- Entrez Gene: 110168 Mouse
- Entrez Gene: 679957 Rat
- Omim: 602042 Human
- SwissProt: Q14330 Human
- SwissProt: Q8K1Z6 Mouse
- SwissProt: A1A5S3 Rat
- Unigene: 741589 Human
see all -
别名
- G protein coupled receptor 18 antibody
- G-protein coupled receptor 18 antibody
- GPCRW antibody
see all
图片
-
Western blot - Anti-GPCR GPR18 antibody [EPR12359] (ab174835)All lanes : Anti-GPCR GPR18 antibody [EPR12359] (ab174835) at 1/1000 dilution
Lane 1 : HuT-78 cell lysate
Lane 2 : 293T cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat anti-rabbit HRP at 1/2000 dilution
Developed using the ECL technique.
Predicted band size: 38 kDa -
![Anti-GPCR GPR18 antibody [EPR12359] (ab174835)](https://www.abcam.cn/ps/products/174/ab174835/Images/ab174835-2-benefits-of-recombinant-antibodies.png)
Anti-GPCR GPR18 antibody [EPR12359] (ab174835)
数据表及文件
-
SDS download
-
Datasheet download
文献 (3)
ab174835 被引用在 3 文献中.
- Lu Q et al. Activation of GPR18 by Resolvin D2 Relieves Pain and Improves Bladder Function in Cyclophosphamide-Induced Cystitis Through Inhibiting TRPV1. Drug Des Devel Ther 15:4687-4699 (2021). PubMed: 34815664
- Remiszewski P et al. Chronic Cannabidiol Administration Fails to Diminish Blood Pressure in Rats with Primary and Secondary Hypertension Despite Its Effects on Cardiac and Plasma Endocannabinoid System, Oxidative Stress and Lipid Metabolism. Int J Mol Sci 21:N/A (2020). PubMed: 32075117
- Zhang MJ et al. Resolvin D2 Enhances Postischemic Revascularization While Resolving Inflammation. Circulation 134:666-80 (2016). PubMed: 27507404