Anti-GPCR GPR17抗体(ab75553)
Key features and details
- Rabbit polyclonal to GPCR GPR17
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-GPCR GPR17抗体
参阅全部 GPCR GPR17 一抗 -
描述
兔多克隆抗体to GPCR GPR17 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide derived from an internal sequence of human GPCR GPR17
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阳性对照
- Extracts from LOVO cells
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS
Without Mg2+ and Ca2+ -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
The antibody was affinity purified from rabbit antiserum by affinity chromatography using epitope immunogen. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab75553于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/1000. Predicted molecular weight: 41 kDa.
|
| 说明 |
|---|
|
WB
1/500 - 1/1000. Predicted molecular weight: 41 kDa. |
靶标
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功能
Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia. -
组织特异性
Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 2840 Human
- Omim: 603071 Human
- SwissProt: Q13304 Human
- Unigene: 46453 Human
- Unigene: 688940 Human
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别名
- DKFZp686M18273 antibody
- G protein coupled receptor 17 antibody
- G-protein coupled receptor 17 antibody
see all
图片
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Western blot - Anti-GPCR GPR17 antibody (ab75553)All lanes : Anti-GPCR GPR17 antibody (ab75553) at 1/500 dilution
Lane 1 : extracts from LOVO cells
Lane 2 : extracts from LOVO cells with immunizing peptide at 5 µg
Lysates/proteins at 10 µg per lane.
Predicted band size: 41 kDa
Observed band size: 41 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab75553 被引用在 1 文献中.
- Luo Q et al. Cangrelor ameliorates CLP-induced pulmonary injury in sepsis by inhibiting GPR17. Eur J Med Res 26:70 (2021). PubMed: 34229761