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AB277142

重组Anti-GOLPH2抗体[024] - BSA and Azide free

Anti-GOLPH2 antibody [024] - BSA and Azide free

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Rabbit Recombinant Monoclonal GOLPH2 antibody. Carrier free. Suitable for Flow Cyt (Intra) and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human GOLM1 aa 1-450.

查看别名

C9orf155, GOLPH2, PSEC0242, UNQ686/PRO1326, GOLM1, Golgi membrane protein 1, Golgi membrane protein GP73, Golgi phosphoprotein 2

1 Images
Flow Cytometry (Intracellular) - Anti-GOLPH2 antibody [024] - BSA and Azide free (AB277142)
  • Flow Cyt (Intra)

Unknown

Flow Cytometry (Intracellular) - Anti-GOLPH2 antibody [024] - BSA and Azide free (AB277142)

Intracellular flow cytometric analysis of GOLPH2 expression on HeLa (human epithelial cell line from cervix adenocarcinoma) cells. The cells were stained with ab277142 at 1/25 dilution then a FITC-conjugated second step antibody. The Fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

024

亚型

IgG

不含载体蛋白

Yes

反应种属

Human

应用

Flow Cyt (Intra)

applications

免疫原

Recombinant Fragment Protein within Human GOLM1 aa 1-450. The exact immunogen used to generate this antibody is proprietary information.

Q8NBJ4

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCytIntra" : {"fullname" : "Flow Cytometry (Intracellular)", "shortname":"Flow Cyt (Intra)"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCytIntra-species-checked": "testedAndGuaranteed", "FlowCytIntra-species-dilution-info": "1/25 - 1/100", "FlowCytIntra-species-notes": "<p></p>" } } }
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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
存储溶液
Constituents: PBS
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
+4°C
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

GOLPH2 also known as GOLM1 or Golgi membrane protein 1 has a significant mechanical role in the cell. It is a 73-kilodalton protein found mainly in the Golgi apparatus. This protein gets expressed in various tissues with notable levels in the liver and other organs involved in secretion. It acts as a transmembrane protein in the Golgi where it helps in processing and sorting secretory proteins influencing how proteins move through secretory pathways.
Biological function summary

GOLPH2 plays an essential role in maintaining Golgi function and efficient protein trafficking. It does not belong to a large protein complex but its proper functioning is critical for handling secretory pathways. The protein keeps secretory flow organized which affects cellular responses and interactions with the environment. The GOLPH2 protein also has connections to immunity responding to stimuli like infections or inflammation.

Pathways

GOLPH2 actively participates in secretory pathways and protein transport systems. Its role includes coordination with other Golgi proteins to facilitate protein modification and sorting. GOLPH2 interacts with other proteins like GOLM1 and GOLPH3 impacting the Golgi's structural organization and influencing pathways like vesicular transport. These interactions are important for adapting the intracellular environment to external demands.

GOLPH2 levels change in diseases such as liver cancer and hepatitis. These changes can serve as biomarkers for diagnosis and disease progression monitoring. GOLPH2 also connects with proteins involved in these diseases including AFP a known tumor marker. Understanding GOLPH2's role in such conditions aids research in developing diagnostic tools and therapeutic strategies.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Unknown. Cellular response protein to viral infection.
See full target information GOLM1
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