Anti-GNAQ抗体(ab128060)
Key features and details
- Goat polyclonal to GNAQ
- Suitable for: WB, IHC-P
- Reacts with: Rat, Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-GNAQ抗体
参阅全部 GNAQ 一抗 -
描述
山羊多克隆抗体to GNAQ -
宿主
Goat -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Rat, Human
预测可用于: Hamster, Cow, Dog, Pig, Monkey, a wide range of other species -
免疫原
Synthetic peptide:
NDLDRVADPAYLPT
with a Cysteine residue linker, corresponding to internal sequence amino acids 162-175 of Human GNAQ. -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab128060于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 38-40 kDa (predicted molecular weight: 42 kDa).
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IHC-P |
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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说明 |
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WB
Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 38-40 kDa (predicted molecular weight: 42 kDa). |
IHC-P
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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功能
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. -
组织特异性
Predominantly expressed in ovary, prostate, testis and colon. -
序列相似性
Belongs to the G-alpha family. G(q) subfamily. - Information by UniProt
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数据库链接
- Entrez Gene: 536654 Cow
- Entrez Gene: 403928 Dog
- Entrez Gene: 2776 Human
- Entrez Gene: 654405 Pig
- Entrez Gene: 81666 Rat
- Omim: 600998 Human
- SwissProt: Q28294 Dog
- SwissProt: P50148 Human
see all -
别名
- CMC1 antibody
- G alpha Q antibody
- G protein alpha Q antibody
see all
图片
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Anti-GNAQ antibody (ab128060) at 0.1 µg/ml + Rat Testis lysate (in RIPA buffer) at 35 µg
Developed using the ECL technique.
Predicted band size: 42 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GNAQ antibody (ab128060)ab128060, at 5 µg/ml, staining GNAQ in paraffin-embedded Human kidney tissue by Immunohistochemistry.
数据表及文件
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SDS download
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Datasheet download
文献 (7)
ab128060 被引用在 7 文献中.
- Goodwin AT et al. Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated TGFβ2 activation. Development 150:N/A (2023). PubMed: 37102682
- Kawakami K et al. Heterotrimeric Gq proteins act as a switch for GRK5/6 selectivity underlying β-arrestin transducer bias. Nat Commun 13:487 (2022). PubMed: 35078997
- Kusumoto J et al. OPN4 belongs to the photosensitive system of the human skin. Genes Cells 25:215-225 (2020). PubMed: 31989708
- Inoue A et al. Illuminating G-Protein-Coupling Selectivity of GPCRs. Cell 177:1933-1947.e25 (2019). PubMed: 31160049
- Chiang NY et al. GPR56/ADGRG1 Activation Promotes Melanoma Cell Migration via NTF Dissociation and CTF-Mediated Ga12/13/RhoA Signaling. J Invest Dermatol 137:727-736 (2017). PubMed: 27818281
- Devost D et al. Conformational Profiling of the AT1 Angiotensin II Receptor Reflects Biased Agonism, G Protein Coupling, and Cellular Context. J Biol Chem 292:5443-5456 (2017). PubMed: 28213525
- Hughes S et al. Using siRNA to define functional interactions between melanopsin and multiple G Protein partners. Cell Mol Life Sci 72:165-79 (2015). IHC . PubMed: 24958088