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AB190555

Anti-GLUT5抗体- N-terminal

Anti-GLUT5 antibody - N-terminal

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(1 Publication)

Rabbit Polyclonal GLUT5 antibody. N-terminal. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human SLC2A5 aa 1-100.

查看别名

GLUT5, SLC2A5, Fructose transporter, GLUT-5

1 Images
Western blot - Anti-GLUT5 antibody - N-terminal (AB190555)
  • WB

Supplier Data

Western blot - Anti-GLUT5 antibody - N-terminal (AB190555)

All lanes:

Western blot - Anti-GLUT5 antibody - N-terminal (ab190555) at 1/500 dilution

All lanes:

K562 cell extract at 30 µg

Predicted band size: 166 kDa,22 kDa,23 kDa,43 kDa,45 kDa,51 kDa,55 kDa

false

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

No

反应种属

Human

应用

WB

applications

免疫原

Synthetic Peptide within Human SLC2A5 aa 1-100. The exact immunogen used to generate this antibody is proprietary information.

P22732

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替代产品

Primary Antibodies

AB41533

Anti-GLUT5 antibody

Western blot - Anti-GLUT5 antibody (AB41533)

  • 1
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Primary Antibodies

AB36057

Anti-GLUT5 antibody

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搭配使用产品

Primary Antibodies

AB115730

Anti-Glucose Transporter GLUT1 antibody [EPR3915]

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Glucose Transporter GLUT1 antibody [EPR3915] (AB115730)

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Primary Antibodies

AB191071

Anti-Glucose Transporter GLUT3 + GLUT14 antibody [EPR10508(N)] - N-terminal

20ul selling size|RabMAb|Recombinant|Trial Size

Western blot - Anti-Glucose Transporter GLUT3 + GLUT14 antibody [EPR10508(N)] - N-terminal (AB191071)

  • 5
  • 6
Primary Antibodies

AB14686

Anti-SGLT1 antibody

Western blot - Anti-SGLT1 antibody (AB14686)

  • 4
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Primary Antibodies

AB54460

Anti-Glucose Transporter GLUT2 antibody

Immunocytochemistry/ Immunofluorescence - Anti-Glucose Transporter GLUT2 antibody (AB54460)

  • 4
  • 9
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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Immunogen
纯化说明
ab190555 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
存储溶液
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

GLUT5 also known as SLC2A5 is a fructose transporter protein that is part of the class II facilitative glucose transporter family. This protein has a molecular mass of approximately 58 kDa. It is highly expressed in the small intestine where it facilitates the uptake of dietary fructose into enterocytes. GLUT5 is also found in other tissues including the kidney testis skeletal muscle and fat tissue but at lower levels.
Biological function summary

GLUT5 plays a vital role in fructose metabolism and energy homeostasis. It functions as a carrier protein mediating the passive transport of fructose along its concentration gradient. GLUT5 does not form a complex with other transporters but works alongside them like GLUT2 which is responsible for fructose export from enterocytes into the bloodstream.

Pathways

GLUT5 is significantly involved in carbohydrate digestion and absorption pathways. It interacts with proteins like GLUT2 during the process of fructose transport across the intestinal epithelium. This functional interaction is key in maintaining normal blood sugar levels and ensuring efficient nutrient absorption post-digestion.

Improper function of GLUT5 relates to fructose malabsorption and metabolic conditions such as obesity. Fructose malabsorption can cause gastrointestinal distress and contribute to irritable bowel syndrome. Furthermore GLUT5 expression studies in obesity link it to other proteins like leptin which influences appetite and energy balance.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Functions as a fructose transporter that has only low activity with other monosaccharides (PubMed : 16186102, PubMed : 17710649, PubMed : 28083649, PubMed : 29548810, PubMed : 8333543). Can mediate the uptake of 2-deoxyglucose, but with low efficiency (PubMed : 1695905). Essential for fructose uptake in the small intestine (By similarity). Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose (By similarity). Required for the development of high blood pressure in response to high dietary fructose intake (By similarity).
See full target information SLC2A5
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 14:603 PubMed36746939

2023

LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice.

Applications

Unspecified application

Species

Unspecified reactive species

Ramachandran Prakasam,Angela Bonadiman,Roberta Andreotti,Emanuela Zuccaro,Davide Dalfovo,Caterina Marchioretti,Debasmita Tripathy,Gianluca Petris,Eric N Anderson,Alice Migazzi,Laura Tosatto,Anna Cereseto,Elena Battaglioli,Gianni Sorarù,Wooi Fang Lim,Carlo Rinaldi,Fabio Sambataro,Naemeh Pourshafie,Christopher Grunseich,Alessandro Romanel,Udai Bhan Pandey,Andrea Contestabile,Giuseppe Ronzitti,Manuela Basso,Maria Pennuto
View all publications
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