AB10551

Anti-GGA1抗体

Name: GGA1抗体 (ab10551)| Abcam中文官网
Brand: Abcam Limited
SKU: AB10551
Price: 2860 CNY
Availability: InStock

Anti-GGA1 antibody

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(2 Publications)

Rabbit Polyclonal GGA1 antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human GGA1 aa 300-400.

查看别名

ADP-ribosylation factor-binding protein GGA1, Gamma-adaptin-related protein 1, GGA1

1 Images

Unknown

Western blot - Anti-GGA1 antibody (AB10551)

The lysate prepared from HEK293 cells overexpressing YFP-GGA1 fusion protein. This accounts for the observed band of 100 kDa.

All lanes:

Western blot - Anti-GGA1 antibody (ab10551) at 1/1350 dilution

All lanes:

Lysate of HEK293 cells overexpressing YFP-GGA1 fusion protein at 35 µg/mL

Secondary

All lanes:

Goat-anti Rabbit IgG

Predicted band size: 70 kDa

Observed band size: 100 kDa

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关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

反应种属

Human

应用

applications

免疫原

Synthetic Peptide within Human GGA1 aa 300-400. The exact immunogen used to generate this antibody is proprietary information.

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特异性

This affinity purified antibody is directed against human GGA1 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest reactivity with this protein from human based on 100% homology for the immunogen sequence. Cross reactivity may occur with GGA1 from bovine (87% homology), mouse (82% homology) and rat (76% homology) sources. The immunizing sequence is present only in isoform 1 of this protein, therefore cross reactivity with splice variants is not expected. Cross reactivity with GGA1 homologues from other sources has not been determined.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" } } }

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification

纯化说明

This affinity purified antibody is directed against human GGA1 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification.

存储溶液

pH: 7.2 Preservative: 0.01% Sodium azide Constituents: 0.88% Sodium chloride, 0.424% Potassium phosphate solution

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif (PubMed : 11301005, PubMed : 15886016). Mediates export of the GPCR receptor ADRA2B to the cell surface (PubMed : 27901063). Required for targeting PKD1 : PKD2 complex from the trans-Golgi network to the cilium membrane (By similarity). Regulates retrograde transport of proteins such as phosphorylated form of BACE1 from endosomes to the trans-Golgi network (PubMed : 15615712, PubMed : 15886016).

See full target information GGA1

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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Traffic (Copenhagen, Denmark) 8:1440-51 PubMed17666033

2007

The Arf GEF GBF1 is required for GGA recruitment to Golgi membranes.

Applications

ICC/IF

Species

African green monkey

Stéphane Lefrançois,Peter J McCormick

The Journal of neuroscience : the official journal of the Society for Neuroscience 26:12838-46 PubMed17151287

2006

GGA1 is expressed in the human brain and affects the generation of amyloid beta-peptide.

Applications

Species

Human

Tina Wahle,Dietmar R Thal,Magdalena Sastre,Andrea Rentmeister,Nenad Bogdanovic,Michael Famulok,Michael T Heneka,Jochen Walter

View all publications

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Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。

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For licensing inquiries, please contact partnerships@abcam.com

Anti-GGA1抗体

Anti-GGA1 antibody

Western blot - Anti-GGA1 antibody (AB10551)

关键信息

宿主种属

克隆

亚型

不含载体蛋白

反应种属

应用

免疫原

特异性