Anti-GDNF Receptor alpha 1/GFRA1抗体(ab8026)
Key features and details
- Rabbit polyclonal to GDNF Receptor alpha 1/GFRA1
- Suitable for: IHC-P, WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-GDNF Receptor alpha 1/GFRA1抗体
参阅全部 GDNF Receptor alpha 1/GFRA1 一抗 -
描述
兔多克隆抗体to GDNF Receptor alpha 1/GFRA1 -
宿主
Rabbit -
经测试应用
适用于: IHC-P, WB, ICC/IFmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide -
Concentration information loading... -
纯度
DEAE-Chromatography -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P | ||
| WB | ||
| ICC/IF |
| 说明 |
|---|
Immunohistochemistry (PFA fixed): 1/50.
WB: 1/500. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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功能
Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. -
序列相似性
Belongs to the GDNFR family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 2674 Human
- Omim: 601496 Human
- SwissProt: P56159 Human
- Unigene: 388347 Human
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别名
- GDNF family receptor alpha 1 antibody
- GDNF family receptor alpha-1 antibody
- GDNF R antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GDNF Receptor alpha 1/GFRA1 antibody (ab8026)
Immunohistochemistry of human brain tissue staining GDNF Receptor alpha 1/GFRA1 using ab8026 at 2.5 μg/ml.
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Immunocytochemistry/ Immunofluorescence - Anti-GDNF Receptor alpha 1/GFRA1 antibody (ab8026)Immunocytochemistry of human brain tissue staining GDNF Receptor alpha 1/GFRA1 using ab8026 at 20 μg/ml.
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Western blot - Anti-GDNF Receptor alpha 1/GFRA1 antibody (ab8026)All lanes : Anti-GDNF Receptor alpha 1/GFRA1 antibody (ab8026) at 1/500 dilution
Lane 1 : Crude membrane fractions of human brain
Lane 2 : Crude membrane fractions of liver
Lane 3 : Crude membrane fractions of kidney
Lane 4 : Crude membrane fractions of spleen
Predicted band size: 50 kDa
Observed band size: 50 kDaWestern blot analysis of GFR alpha 1/GFRA1 in crude membrane fractions of human brain (B), liver (L), kidney (K), and spleen (S), respectively, with ab8026 at 1/500 dilution.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GDNF Receptor alpha 1/GFRA1 antibody (ab8026)Immunohistochemistry of human brain tissue staining GDNF Receptor alpha 1/GFRA1 using ab8026 at 1 μg/ml.
数据表及文件
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Datasheet download
文献 (18)
ab8026 被引用在 18 文献中.
- Jung SE et al. Autophagy modulation alleviates cryoinjury in murine spermatogonial stem cell cryopreservation. Andrology 10:340-353 (2022). PubMed: 34499811
- Vargova I et al. Long-Term Cultures of Spinal Cord Interneurons. Front Cell Neurosci 16:827628 (2022). PubMed: 35197829
- Liu W et al. Role of GDNF, GFRα1 and GFAP in a Bifidobacterium-Intervention Induced Mouse Model of Intestinal Neuronal Dysplasia. Front Pediatr 9:795678 (2021). PubMed: 35096711
- Jung SE et al. Inhibition of Caspase-8 Activity Improves Freezing Efficiency of Male Germline Stem Cells in Mice. Biopreserv Biobank N/A:N/A (2021). PubMed: 33926212
- Jung SE et al. Antioxidant or Apoptosis Inhibitor Supplementation in Culture Media Improves Post-Thaw Recovery of Murine Spermatogonial Stem Cells. Antioxidants (Basel) 10:N/A (2021). PubMed: 34068575
