重组Anti-GDI1抗体[EPR13196(B)] (ab175194)
![Western blot - Anti-GDI1 antibody [EPR13196(B)] (ab175194)](https://www.abcam.cn/ps/products/175/ab175194/Images/ab175194-201533-ab1751941.jpg "Western blot - Anti-GDI1 antibody [EPR13196(B)] (ab175194)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR13196(B)] to GDI1
- Suitable for: Flow Cyt (Intra), WB
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-GDI1抗体[EPR13196(B)]
参阅全部 GDI1 一抗 -
描述
兔单克隆抗体[EPR13196(B)] to GDI1 -
宿主
Rabbit -
经测试应用
适用于: Flow Cyt (Intra), WBmore details
不适用于: ICC/IF,IHC-P or IP -
种属反应性
与反应: Human
预测可用于: Mouse, Rat
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免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- U87-MG, HeLa, SH-SY5Y and Human fetal brain lysates; Permeabilized SH-SY5Y cells.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading... -
纯度
Tissue culture supernatant -
克隆
单克隆 -
克隆编号
EPR13196(B) -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab175194于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt (Intra) |
1/10 - 1/100.
ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody. |
|
| WB |
1/10000 - 1/50000. Predicted molecular weight: 51 kDa.
|
| 说明 |
|---|
|
Flow Cyt (Intra)
1/10 - 1/100. ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody. |
|
WB
1/10000 - 1/50000. Predicted molecular weight: 51 kDa. |
靶标
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功能
Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. -
组织特异性
Brain; predominant in neural and sensory tissues. -
疾病相关
Defects in GDI1 are the cause of mental retardation X-linked type 41 (MRX41) [MIM:300104]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
Defects in GDI1 are the cause of mental retardation X-linked type 48 (MRX48) [MIM:300104]; also known as MRX3. -
序列相似性
Belongs to the Rab GDI family. -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 2664 Human
- Entrez Gene: 14567 Mouse
- Entrez Gene: 25183 Rat
- Omim: 300104 Human
- SwissProt: P31150 Human
- SwissProt: P50396 Mouse
- SwissProt: P50398 Rat
- Unigene: 74576 Human
see all -
别名
- 1A antibody
- FLJ41411 antibody
- GDI-1 antibody
see all
图片
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Western blot - Anti-GDI1 antibody [EPR13196(B)] (ab175194)All lanes : Anti-GDI1 antibody [EPR13196(B)] (ab175194) at 1/10000 dilution
Lane 1 : U87-MG lysates
Lane 2 : HeLa lysates
Lane 3 : SH-SY5Y lysates
Lane 4 : Human fetal brain lysates
Lysates/proteins at 10 µg per lane.
Predicted band size: 51 kDa -
![Flow Cytometry (Intracellular) - Anti-GDI1 antibody [EPR13196(B)] (ab175194)](https://www.abcam.cn/ps/products/175/ab175194/Images/ab175194-201532-ab1751942.jpg)
Flow Cytometry (Intracellular) - Anti-GDI1 antibody [EPR13196(B)] (ab175194)Intracellular flow cytometric analysis of permeabilized SH-SY5Ycells labeling GDI1 with ab175194at 1/10 dilution (red)or a Rabbit IgG (negative) (green).
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![Anti-GDI1 antibody [EPR13196(B)] (ab175194)](https://www.abcam.cn/ps/products/175/ab175194/Images/ab175194-3-benefits-of-recombinant-antibodies.png)
Anti-GDI1 antibody [EPR13196(B)] (ab175194)
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab175194 尚未被引用在任何文献中。