重组Anti-GDF15抗体[EPR6982(2)] (ab180929)
![Western blot - Anti-GDF15 antibody [EPR6982(2)] (ab180929)](https://www.abcam.cn/ps/products/180/ab180929/Images/ab180929-214854-anti-gdf15-antibody-epr69822-western-blot.jpg "Western blot - Anti-GDF15 antibody [EPR6982(2)] (ab180929)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR6982(2)] to GDF15
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-GDF15抗体[EPR6982(2)]
参阅全部 GDF15 一抗 -
描述
兔单克隆抗体[EPR6982(2)] to GDF15 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- LnCap and HepG2 cell lysates.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol, 0.05% BSA -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR6982(2) -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab180929于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000 - 1/10000. Detects a band of approximately 35 kDa (predicted molecular weight: 34 kDa).
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| 说明 |
|---|
|
WB
1/1000 - 1/10000. Detects a band of approximately 35 kDa (predicted molecular weight: 34 kDa). |
靶标
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组织特异性
Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney. -
序列相似性
Belongs to the TGF-beta family. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 9518 Human
- Omim: 605312 Human
- SwissProt: Q99988 Human
- Unigene: 616962 Human
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别名
- GDF 15 antibody
- GDF-15 antibody
- Gdf15 antibody
see all
图片
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Western blot - Anti-GDF15 antibody [EPR6982(2)] (ab180929)Anti-GDF15 antibody [EPR6982(2)] (ab180929) at 1/1000 dilution + HepG2 cell lysate at 10 µg
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase Conjugate at 1/1000 dilution
Predicted band size: 34 kDa -
![Western blot - Anti-GDF15 antibody [EPR6982(2)] (ab180929)](https://www.abcam.cn/ps/products/180/ab180929/Images/ab180929-214853-anti-gdf15-antibody-epr69822-western-blot.jpg)
Western blot - Anti-GDF15 antibody [EPR6982(2)] (ab180929)Anti-GDF15 antibody [EPR6982(2)] (ab180929) at 1/5000 dilution + LnCap cell lysate at 10 µg
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution
Predicted band size: 34 kDa -
![Anti-GDF15 antibody [EPR6982(2)] (ab180929)](https://www.abcam.cn/ps/products/180/ab180929/Images/ab180929-3-benefits-of-recombinant-antibodies.png)
Anti-GDF15 antibody [EPR6982(2)] (ab180929)
数据表及文件
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SDS download
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Datasheet download
Certificate of Compliance
文献 (4)
ab180929 被引用在 4 文献中.
- Zhou L et al. Extracellular Vesicles Derived from Human Bone Marrow Stem Cells Inhibit Acute Lymphoblastic Leukemia Cell Growth by Inhibiting MAPK Pathway via the miR-29b-3p/GDF15 Axis. Acta Haematol 146:504-516 (2023). PubMed: 36327876
- Lu JF et al. Camptothecin effectively treats obesity in mice through GDF15 induction. PLoS Biol 20:e3001517 (2022). PubMed: 35202387
- Tian Q et al. Development and Validation of a Ferroptosis-Related Gene Signature for Overall Survival Prediction in Lung Adenocarcinoma. Front Cell Dev Biol 9:684259 (2021). PubMed: 34307361
- Zhao C et al. C5a induces A549 cell proliferation of non-small cell lung cancer via GDF15 gene activation mediated by GCN5-dependent KLF5 acetylation. Oncogene 37:4821-4837 (2018). PubMed: 29773900