Anti-GDF15抗体(ab105738)
Key features and details
- Rabbit polyclonal to GDF15
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
概述
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产品名称
Anti-GDF15抗体
参阅全部 GDF15 一抗 -
描述
兔多克隆抗体to GDF15 -
宿主
Rabbit -
特异性
A BLAST analysis suggests reactivity with NAG-1 from rat based on 100% homology. Partial reactivity is expected against swine, bovine and dog based on 92% homology. Cross-reactivity with NAG-1 from other sources has not been determined.
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经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse, Human
预测可用于: Rat, Cow, Dog, Pig
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免疫原
Synthetic peptide corresponding to amino acids near the C-terminal of Mouse GDF15.
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常规说明
Expiration date is one (1) year from date of opening product.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 0.424% Potassium phosphate solution, 0.88% Sodium chloride -
Concentration information loading... -
纯度
Affinity purified -
纯化说明
This product was affinity purified from monospecific antiserum by immunoaffinity chromatography. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab105738于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/3000 - 1/7000. Predicted molecular weight: 33 kDa.
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| 说明 |
|---|
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WB
1/3000 - 1/7000. Predicted molecular weight: 33 kDa. |
靶标
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组织特异性
Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney. -
序列相似性
Belongs to the TGF-beta family. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 618677 Cow
- Entrez Gene: 9518 Human
- Entrez Gene: 23886 Mouse
- Entrez Gene: 29455 Rat
- Omim: 605312 Human
- SwissProt: Q99988 Human
- SwissProt: Q9Z0J7 Mouse
- SwissProt: Q9Z0J6 Rat
see all -
别名
- GDF 15 antibody
- GDF-15 antibody
- Gdf15 antibody
see all
图片
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Western blot - Anti-GDF15 antibody (ab105738)All lanes : Anti-GDF15 antibody (ab105738) at 1/1000 dilution
Lane 1 : Recombinant MBP-GDF15 fusion protein purified from E.coli
Lane 2 : Yeast cell lysate expressing SUMO-Mouse GDF15
Lane 3 : Human GDF15 monomer purified from CHO-K1 cells
Secondary
All lanes : Goat-anti-Rabbit HRP at 1/40000 dilution
Performed under reducing conditions.
Predicted band size: 33 kDa
Expect bands in Western blots of approximately 14 and 28 kDa in size corresponding to GDF15 monomer and dimer, respectively.
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab105738 被引用在 2 文献中.
- Patsalos A et al. A growth factor-expressing macrophage subpopulation orchestrates regenerative inflammation via GDF-15. J Exp Med 219:N/A (2022). PubMed: 34846534
- Weng JH et al. Colchicine acts selectively in the liver to induce hepatokines that inhibit myeloid cell activation. Nat Metab 3:513-522 (2021). PubMed: 33846641