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AB126167

Anti-GCSF Receptor 抗体

Anti-GCSF Receptor antibody

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(7 Publications)

Rabbit Polyclonal GCSF Receptor antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 7 publications. Immunogen corresponding to Recombinant Fragment Protein within Human CSF3R aa 150-400.

查看别名

CD114, GCSFR, CSF3R, Granulocyte colony-stimulating factor receptor, G-CSF receptor, G-CSF-R

3 Images
Immunocytochemistry/ Immunofluorescence - Anti-GCSF Receptor antibody (AB126167)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-GCSF Receptor antibody (AB126167)

Immunofluorescence analysis of THP-1 (human monocytic leukemia cell line) cells labeling GCSF Receptor (green) using ab126167 at 1/500 dilution. Blue : Mounting medium with DAPI. Sample : THP-1 cells were fixed in 4% paraformaldehyde at RT for 15 min.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GCSF Receptor antibody (AB126167)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GCSF Receptor antibody (AB126167)

Formalin-fixed, paraffin embedded human breast carcinoma tissue stained fro GCSF receptor usinf a126167 at 1/250 dilution in immunohistochemical analysis,

Antigen Retrieval : EDTA based, pH 8.0 buffer, 15min

Western blot - Anti-GCSF Receptor antibody (AB126167)
  • WB

Supplier Data

Western blot - Anti-GCSF Receptor antibody (AB126167)

7.5% SDS-PAGE

All lanes:

Western blot - Anti-GCSF Receptor antibody (ab126167) at 1/500 dilution

Lane 1:

Non-transfected HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate at 30 µg

Lane 2:

Transfected HEK-293T whole cell lysate at 30 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

Predicted band size: 92 kDa

false

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

No

反应种属

Human

应用

IHC-P, ICC/IF, WB

applications

免疫原

Recombinant Fragment Protein within Human CSF3R aa 150-400. The exact immunogen used to generate this antibody is proprietary information.

Q99062

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100.00000 - 1/1000.00000", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500.00000 - 1/3000.00000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100.00000 - 1/1000.00000", "ICCIF-species-notes": "<p></p>" } } }
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为什么推荐这个？

我们推荐这个产品，因为它经常被用于相同的实验或相关的研究。

我们建议您务必查阅产品说明书，以确认其是否符合您的实验需求；若有疑问，也可联系我们的技术团队获取协助。

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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Immunogen
存储溶液
pH: 7 Preservative: 0.025% Proclin 300 Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine)
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differentiation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface.
See full target information CSF3R
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文献 (7)

Recent publications for all applications. Explore the full list and refine your search

BMC oral health 23:422 PubMed37365568

2023

Effects of G-CSF on hPDLSC proliferation and osteogenic differentiation in the LPS-induced inflammatory microenvironment.

Applications

Unspecified application

Species

Unspecified reactive species

Hui Yu,Pengcheng Wang,Haibin Lu,Jiurong Guan,Fang Yao,Tianyi Zhang,Qiuxu Wang,Zuomin Wang

Frontiers in cell and developmental biology 8:601043 PubMed33415106

2020

Vitamin D Promotes Trophoblast Cell Induced Separation of Vascular Smooth Muscle Cells in Vascular Remodeling Induction of G-CSF.

Applications

Unspecified application

Species

Unspecified reactive species

Joy Yue Zhang,Peihuang Wu,Danyang Chen,Fen Ning,Qinsheng Lu,Xiu Qiu,Martin Hewison,Jennifer A Tamblyn,Mark D Kilby,Gendie E Lash

Scientific data 6:21 PubMed30967555

2019

Phospho serine and threonine analysis of normal and mutated granulocyte colony stimulating factor receptors.

Applications

Unspecified application

Species

Unspecified reactive species

Pankaj Dwivedi,David E Muench,Michael Wagner,Mohammad Azam,H Leighton Grimes,Kenneth D Greis

Haematologica 104:1789-1797 PubMed30819912

2019

mutations are recurrently acquired during chronic myeloid leukemia progression and interfere with myeloid differentiation pathways.

Applications

Unspecified application

Species

Unspecified reactive species

Vera Magistroni,Mario Mauri,Deborah D'Aliberti,Caterina Mezzatesta,Ilaria Crespiatico,Miriam Nava,Diletta Fontana,Nitesh Sharma,Wendy Parker,Andreas Schreiber,David Yeung,Alessandra Pirola,Sara Readelli,Luca Massimino,Paul Wang,Praveen Khandelwal,Stefania Citterio,Michela Viltadi,Silvia Bombelli,Roberta Rigolio,Roberto Perego,Jacqueline Boultwood,Alessandro Morotti,Giuseppe Saglio,Dong-Wook Kim,Susan Branford,Carlo Gambacorti-Passerini,Rocco Piazza

Cancer research 77:4258-4267 PubMed28652245

2017

Unpaired Extracellular Cysteine Mutations of CSF3R Mediate Gain or Loss of Function.

Applications

Unspecified application

Species

Unspecified reactive species

Haijiao Zhang,Sophie Means,Anna Reister Schultz,Kevin Watanabe-Smith,Bruno C Medeiros,Daniel Bottomly,Beth Wilmot,Shannon K McWeeney,Tim Kükenshöner,Oliver Hantschel,Jeffrey W Tyner

Clinical cancer research : an official journal of the American Association for Cancer Research 22:757-64 PubMed26475333

2015

The Colony-Stimulating Factor 3 Receptor T640N Mutation Is Oncogenic, Sensitive to JAK Inhibition, and Mimics T618I.

Applications

WB

Species

Human

Julia E Maxson,Samuel B Luty,Jason D MacManiman,Jason C Paik,Jason Gotlib,Peter Greenberg,Swaleh Bahamadi,Samantha L Savage,Melissa L Abel,Christopher A Eide,Marc M Loriaux,Emily A Stevens,Jeffrey W Tyner

The Journal of biological chemistry 289:5820-7 PubMed24403076

2014

Ligand independence of the T618I mutation in the colony-stimulating factor 3 receptor (CSF3R) protein results from loss of O-linked glycosylation and increased receptor dimerization.

Applications

WB

Species

Human

Julia E Maxson,Samuel B Luty,Jason D MacManiman,Melissa L Abel,Brian J Druker,Jeffrey W Tyner
View all publications
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详情请参阅我们的条款与条件。
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