AB181839

重组Anti-GCLC抗体[EPR13476(B)]

Name: GCLC抗体[EPR13476(B)] (ab181839)| Abcam中文官网
Brand: Abcam Limited
SKU: AB181839
Price: 2883 CNY
Availability: InStock
Rating: 3 (1 reviews)

Anti-GCLC antibody [EPR13476(B)]

RabMAb
Recombinant
了解详情

(1 Review)

(3 Publications)

Rabbit Recombinant Monoclonal GCLC antibody. Suitable for WB and reacts with Human samples. Cited in 3 publications.

查看别名

GLCL, GLCLC, GCLC, Glutamate--cysteine ligase catalytic subunit, GCS heavy chain, Gamma-ECS, Gamma-glutamylcysteine synthetase

2 Images

Supplier Data

Western blot - Anti-GCLC antibody [EPR13476(B)] (AB181839)

All lanes:

Western blot - Anti-GCLC antibody [EPR13476(B)] (ab181839) at 1/5000 dilution

All lanes:

HepG2 cell lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Predicted band size: 73 kDa

Observed band size: 73 kDa

false

Supplier Data

Western blot - Anti-GCLC antibody [EPR13476(B)] (AB181839)

All lanes:

Western blot - Anti-GCLC antibody [EPR13476(B)] (ab181839) at 1/10000 dilution

Lane 1:

Human fetal liver lysate at 10 µg

Lane 2:

A549 cell lysate at 10 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Predicted band size: 73 kDa

Observed band size: 73 kDa

false

不同偶联物与剂型 (1)

Carrier free

Anti-GCLC antibody [EPR13476(B)] - BSA and Azide free

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR13476(B)

亚型

IgG

不含载体蛋白

反应种属

Human

应用

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

style

left-column

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

style

left-column

产品详情

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

style

left-column

性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Protein A

存储溶液

Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

style

left-column

style

left-column

style

left-column

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

靶点信息

Catalyzes the ATP-dependent ligation of L-glutamate and L-cysteine and participates in the first and rate-limiting step in glutathione biosynthesis.

See full target information GCLC

style

left-column

文献 (3)

Recent publications for all applications. Explore the full list and refine your search

Microbial cell (Graz, Austria) 10:157-169 PubMed37545643

2023

Caspase 3 exhibits a yeast metacaspase proteostasis function that protects mitochondria from toxic TDP43 aggregates.

Applications

Unspecified application

Species

Unspecified reactive species

Steve Brunette,Anupam Sharma,Ryan Bell,Lawrence Puente,Lynn A Megeney

Neurochemical research 48:2542-2551 PubMed37061657

2023

Dithiolethiones D3T and ACDT Protect Against Iron Overload-Induced Cytotoxicity and Serve as Ferroptosis Inhibitors in U-87 MG Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Neha Kulkarni,Rajitha Gadde,Swati Betharia

American journal of cancer research 11:2911-2927 PubMed34249435

2021

Glutamate-cysteine ligase catalytic subunit as a therapeutic target in acute myeloid leukemia and solid tumors.

Applications

Unspecified application

Species

Unspecified reactive species

Chiou-Hong Lin,John P Vu,Chen-Yen Yang,Mint Sirisawad,Chun-Te Chen,Hung Dao,Jing Liu,Xuan Ma,Chin Pan,Joseph Cefalu,Chris Tse,Erica Jackson,Hsu-Ping Kuo

View all publications

style

left-column

Anti-GCLC antibody [EPR13476(B)]

Western blot - Anti-GCLC antibody [EPR13476(B)] (AB181839)

Western blot - Anti-GCLC antibody [EPR13476(B)] (AB181839)

不同偶联物与剂型 (1)

关键信息

宿主种属

克隆

克隆号

亚型

不含载体蛋白

反应种属

应用

免疫原

反应性数据

产品详情

性能和储存信息

形式

纯化工艺

存储溶液

运输条件

推荐的短期储存时间

推荐的短期储存条件

推荐的长期储存条件

分装信息

储存信息

产品实验方案

靶点信息

文献 (3)

Abcam Product Promise