Anti-GATA3抗体[KT77] (ab110093)
Key features and details
- Rat monoclonal [KT77] to GATA3
- Suitable for: WB, ICC/IF
- Reacts with: Mouse
- Isotype: IgG2a
概述
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产品名称
Anti-GATA3抗体[KT77]
参阅全部 GATA3 一抗 -
描述
大鼠单克隆抗体[KT77] to GATA3 -
宿主
Rat -
经测试应用
适用于: WB, ICC/IFmore details -
种属反应性
与反应: Mouse -
免疫原
Full length protein corresponding to Mouse GATA3.
Database link: P23772 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
KT77 -
同种型
IgG2a -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab110093于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/500 - 1/10000. Predicted molecular weight: 47 kDa.
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ICC/IF |
1/100 - 1/1000.
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说明 |
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WB
1/500 - 1/10000. Predicted molecular weight: 47 kDa. |
ICC/IF
1/100 - 1/1000. |
靶标
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功能
Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. -
组织特异性
T-cells and endothelial cells. -
疾病相关
Defects in GATA3 are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia (HDR) [MIM:146255]; also known as Barakat syndrome. -
序列相似性
Contains 2 GATA-type zinc fingers. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 14462 Mouse
- SwissProt: P23772 Mouse
- Unigene: 313866 Mouse
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形式
There are 2 isoforms produced by alternative splicing. -
别名
- GATA 3 antibody
- GATA binding factor 3 antibody
- GATA binding protein 3 antibody
see all
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab110093 被引用在 3 文献中.
- Sun F et al. Interleukin-33 increases type 2 innate lymphoid cell count and their activation in eosinophilic asthma. Clin Transl Allergy 13:e12265 (2023). PubMed: 37357549
- Bi CS et al. Calcitriol inhibits osteoclastogenesis in an inflammatory environment by changing the proportion and function of T helper cell subsets (Th2/Th17). Cell Prolif 53:e12827 (2020). PubMed: 32406154
- Newland SA et al. Type-2 innate lymphoid cells control the development of atherosclerosis in mice. Nat Commun 8:15781 (2017). IHC-Fr ; Mouse . PubMed: 28589929