Anti-GALNT9抗体(ab172528)
Key features and details
- Rabbit polyclonal to GALNT9
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-GALNT9抗体 -
描述
兔多克隆抗体to GALNT9 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat
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免疫原
Recombinant full length protein corresponding to Human GALNT9 aa 1-247. Isoform 2
Sequence:MEVLPCSRVAHIERTRKPYNNDIDYYAKRNALRAAEVWMDDFKSHVYMAW NIPMSNPGVDFGDVSERLALRQRLKCRSFKWYLENVYPEMRVYNNTLTYG EVRNSKASAYCLDQGAEDGDRAILYPCHGMSSQLVRYSADGLLQLGPLGS TAFLPDSKCLVDDGTGRMPTLKKCEDVARPTQRLWDFTQSGPIVSRATGR CLEVEMSKDANFGLRLVVQRCSGQKWMIRNWIKHARH
Database link: NP_068580.2 -
阳性对照
- GALNT9 transfected 293T cell line lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.4
Constituent: 100% PBS -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab172528于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 68 kDa.
|
| 说明 |
|---|
|
WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 68 kDa. |
靶标
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功能
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Does not glycosylate apomucin or SDC3. -
组织特异性
Specifically expressed in brain. Not expressed in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte. In brain, it is expressed in cerebellum, frontal lobe, temporal lobe, putamen and spinal cord, weakly expressed in cerebral cortex. Not expressed in medulla and occipital pole. -
通路
Protein modification; protein glycosylation. -
序列相似性
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
Contains 1 ricin B-type lectin domain. -
结构域
There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity. -
细胞定位
Golgi apparatus membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 50614 Human
- Entrez Gene: 231605 Mouse
- Entrez Gene: 304571 Rat
- Omim: 606251 Human
- SwissProt: Q9HCQ5 Human
- Unigene: 301062 Human
- Unigene: 658249 Human
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别名
- GalNAc T9 antibody
- GalNAc transferase 9 antibody
- GalNAc-T9 antibody
see all
图片
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Western blot - Anti-GALNT9 antibody (ab172528)All lanes : Anti-GALNT9 antibody (ab172528) at 1 µg/ml
Lane 1 : GALNT9 transfected 293T cell line lysate
Lane 2 : Non-transfected 293T cell line lysate
Lysates/proteins at 15 µg/ml per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG (H+L), Peroxidase Conjugated at 1/2500 dilution
Predicted band size: 68 kDa
数据表及文件
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Datasheet download
文献 (0)
ab172528 尚未被引用在任何文献中。
