Anti-GADD45A抗体(ab180768)
Key features and details
- Rabbit polyclonal to GADD45A
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
概述
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产品名称
Anti-GADD45A抗体 -
描述
兔多克隆抗体to GADD45A -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse
预测可用于: Cow, Cat, Chinese hamster
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免疫原
Recombinant full length protein corresponding to Human GADD45A aa 1-165.
Sequence:MTLEEFSAGE QKTERMDKVG DALEEVLSKA LSQRTITVGV YEAAKLLNVD PDNVVLCLLA ADEDDDRDVA LQIHFTLIQA FCCENDINIL RVSNPGRLAE LLLLETDAGP AASEGAEQPP DLHCVLVTNP HSSQWKDPAL SQLICFCRES RYMDQWVPVI NLPERLE
Database link: P24522 -
阳性对照
- WB: Mouse liver tissue lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.30
Preservative: 0.09% Sodium azide
Constituents: 49.91% PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab180768于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | (1) |
1/500 - 1/2000. Predicted molecular weight: 18 kDa.
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| 说明 |
|---|
|
WB
1/500 - 1/2000. Predicted molecular weight: 18 kDa. |
靶标
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功能
Binds to proliferating cell nuclear antigen. Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. -
序列相似性
Belongs to the GADD45 family. - Information by UniProt
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数据库链接
- Entrez Gene: 493656 Cat
- Entrez Gene: 505463 Cow
- Entrez Gene: 13197 Mouse
- SwissProt: Q60GI5 Cat
- SwissProt: P24523 Chinese hamster
- SwissProt: Q3ZBN6 Cow
- SwissProt: P48316 Mouse
- Unigene: 72235 Mouse
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别名
- DDIT 1 antibody
- DDIT-1 antibody
- DDIT1 antibody
see all
图片
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Western blot - Anti-GADD45A antibody (ab180768)Anti-GADD45A antibody (ab180768) at 1/1000 dilution + Extracts of mouse liver at 25 µg
Secondary
HRP Goat Anti-Rabbit IgG
Developed using the ECL technique.
Predicted band size: 18 kDa
Exposure time: 90 secondsBlocking buffer: 3% nonfat dry milk in TBST.
数据表及文件
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SDS download
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Datasheet download
文献 (21)
ab180768 被引用在 21 文献中.
- Yan X et al. Lenvatinib inhibits intrahepatic cholangiocarcinoma via Gadd45a-mediated cell cycle arrest. Discov Oncol 14:26 (2023). PubMed: 36821012
- Peng C et al. Function of DHX33 in promoting Warburg effect via regulation of glycolytic genes. J Cell Physiol 236:981-996 (2021). PubMed: 32617965
- Yang Y & Shang H Silencing lncRNA-DGCR5 increased trophoblast cell migration, invasion and tube formation, and inhibited cell apoptosis via targeting miR-454-3p/GADD45A axis. Mol Cell Biochem 476:3407-3421 (2021). PubMed: 33973132
- Yang C et al. Circular RNA RBPMS inhibits bladder cancer progression via miR-330-3p/RAI2 regulation. Mol Ther Nucleic Acids 23:872-886 (2021). PubMed: 33614236
- Zhang YL et al. Progesterone suppresses the progression of colonic carcinoma by increasing the activity of the GADD45a/JNK/c-Jun signalling pathway. Oncol Rep 45:N/A (2021). PubMed: 33846816