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Anti-GABA A Receptor beta 3/GABRB3抗体(ab66430)

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Key features and details

  • Rabbit polyclonal to GABA A Receptor beta 3/GABRB3
  • Suitable for: IHC-Fr, IHC-P, Flow Cyt, ELISA, WB
  • Reacts with: Human
  • Isotype: IgG

概述

  • 产品名称

    Anti-GABA A Receptor beta 3/GABRB3抗体
    参阅全部 GABA A Receptor beta 3/GABRB3 一抗

  • 描述

    兔多克隆抗体to GABA A Receptor beta 3/GABRB3

  • 宿主

    Rabbit

  • 经测试应用

    适用于: IHC-Fr, IHC-P, Flow Cyt, ELISA, WBmore details

  • 种属反应性

    与反应: Human
    预测可用于: Mouse, Rat

  • 免疫原

    Synthetic peptide corresponding to Human GABA A Receptor beta 3/GABRB3 (N terminal).

  • 常规说明

    We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result, we are pleased to offer this antibody in a purified format as of 23rd June 2017. The following lots are still unpurified and still in stock as of 23rd June 2017 - GR325257-1, GR325257-2, GR325257-3, GR325257-4, GR325257-5, GR325257-6, GR1530-9, GR1530-10. Lot numbers other than GR325257-1, GR325257-2, GR325257-3, GR325257-4, GR325257-5, GR325257-6, GR1530-9, GR1530-10 will be purified. Please note that the dilutions may need to be adjusted accordingly. Purified antibodies have the advantage of being enriched for the fraction of immunoglobulin that specifically reacts with the target antigen and for having a reduction of serum proteins.

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

性能

应用

The Abpromise guarantee

Abpromise™承诺保证使用ab66430于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

应用 Ab评论 说明
IHC-Fr
Use at an assay dependent concentration.
IHC-P
Use at an assay dependent concentration.
Flow Cyt
Use at an assay dependent concentration. PubMed: 22563490

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
ELISA
Use at an assay dependent concentration. PubMed: 22563490
WB
Use at an assay dependent concentration.
说明
IHC-Fr
Use at an assay dependent concentration.
IHC-P
Use at an assay dependent concentration.
Flow Cyt
Use at an assay dependent concentration. PubMed: 22563490

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
ELISA
Use at an assay dependent concentration. PubMed: 22563490
WB
Use at an assay dependent concentration.

靶标

  • 功能

    Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.

  • 疾病相关

    Epilepsy, childhood absence 5

  • 序列相似性

    Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB3 sub-subfamily.

  • 细胞定位

    Cell junction, synapse, postsynaptic cell membrane. Cell membrane.
  • Information by UniProt

  • 数据库链接

    see all

  • 别名

    • ECA5 antibody
    • GABA alpha receptor beta-2 subunit antibody
    • GABA(A) receptor subunit beta-3 antibody
    • GABAA receptor beta 3 subunit antibody
    • GABAA receptor subunit beta 3 antibody
    • GABR B3 antibody
    • Gabrb3 antibody
    • Gamma aminobutyric acid (GABA) A receptor beta 3 antibody
    • Gamma aminobutyric acid receptor subunit beta 3 antibody
    • Gamma-aminobutyric acid receptor subunit beta-3 antibody
    • GBRB3_HUMAN antibody
    • MGC9051 antibody
    see all

文献 (1)

发表研究结果有使用 ab66430？请让我们知道，以便我们可以引用本数据表中的参考文章。

ab66430 被引用在 1 文献中.

  • Desrues L  et al. Down-regulation of GABA(A) receptor via promiscuity with the vasoactive peptide urotensin II receptor. Potential involvement in astrocyte plasticity. PLoS One 7:e36319 (2012). ELISA, Flow Cyt ; Human . PubMed: 22563490

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