Anti-FPRL1/RFP抗体(ab63023)
Key features and details
- Rabbit polyclonal to FPRL1/RFP
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-FPRL1/RFP抗体
参阅全部 FPRL1/RFP 一抗 -
描述
兔多克隆抗体to FPRL1/RFP -
宿主
Rabbit -
经测试应用
适用于: WB, ICC/IFmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human FPRL1/RFP (C terminal) conjugated to keyhole limpet haemocyanin.
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阳性对照
- HL60 cells and HL60 cell extract.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.0268% PBS, 50% Glycerol, 0.01% BSA -
Concentration information loading... -
纯度
Protein G purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab63023于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | (1) |
1/6000. Detects a band of approximately 38 kDa (predicted molecular weight: 39 kDa).
|
| ICC/IF |
1/600.
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| 说明 |
|---|
|
WB
1/6000. Detects a band of approximately 38 kDa (predicted molecular weight: 39 kDa). |
|
ICC/IF
1/600. |
靶标
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功能
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). -
组织特异性
Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 2358 Human
- Omim: 136538 Human
- SwissProt: P25090 Human
- Unigene: 99855 Human
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别名
- ALXR antibody
- FMLP-R-I antibody
- FMLP-R-II antibody
see all
图片
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Western blot - Anti-FPRL1/RFP antibody (ab63023)Anti-FPRL1/RFP antibody (ab63023) at 1/6000 dilution + Extracts of HL60 cells
Predicted band size: 39 kDa
Observed band size: 38 kDa why is the actual band size different from the predicted? -
Immunocytochemistry/ Immunofluorescence - Anti-FPRL1/RFP antibody (ab63023)Immunofluorescent analysis of HL60 cells using ab63023 (green) at 1:600. Nucleus have been labeled with PI (red).
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab63023 被引用在 1 文献中.
- Xu C et al. CSA13 inhibits colitis-associated intestinal fibrosis via a formyl peptide receptor like-1 mediated HMG-CoA reductase pathway. Sci Rep 7:16351 (2017). PubMed: 29180648