FITC荧光Anti-Interferon gamma抗体[CC302] (ab27865)
Key features and details
- FITC Mouse monoclonal [CC302] to Interferon gamma
- Suitable for: Flow Cyt
- Reacts with: Sheep, Goat, Horse, Cow, Dog, Human, Pig, Ferret
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
概述
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产品名称
FITC荧光Anti-Interferon gamma抗体[CC302]
参阅全部 Interferon gamma 一抗 -
描述
FITC荧光小鼠单克隆抗体[CC302] to Interferon gamma -
宿主
Mouse -
偶联物
FITC. Ex: 493nm, Em: 528nm -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Sheep, Goat, Horse, Cow, Dog, Human, Pig, Ferret -
免疫原
The details of the immunogen for this antibody are not available.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.40
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading... -
纯度
Protein G purified -
纯化说明
This antibody was purified by affinity chromatography from tissue culture supernatant. -
克隆
单克隆 -
克隆编号
CC302 -
骨髓瘤
Sp2/0 -
同种型
IgG1 -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab27865于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt |
1/10.
ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. Use 10µl of the suggested working dilution to label 106 cells in 100µl. Membrane permeabilisation is required for this application. |
| 说明 |
|---|
|
Flow Cyt
1/10. ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. Use 10µl of the suggested working dilution to label 106 cells in 100µl. Membrane permeabilisation is required for this application. |
靶标
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功能
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. -
组织特异性
Released primarily from activated T lymphocytes. -
疾病相关
In Caucasians, genetic variation in IFNG is associated with the risk of aplastic anemia (AA) [MIM:609135]. AA is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis. -
序列相似性
Belongs to the type II (or gamma) interferon family. -
翻译后修饰
Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 281237 Cow
- Entrez Gene: 403801 Dog
- Entrez Gene: 100860815 Goat
- Entrez Gene: 100034181 Horse
- Entrez Gene: 3458 Human
- Entrez Gene: 396991 Pig
- Entrez Gene: 443396 Sheep
- Omim: 147570 Human
see all -
别名
- IF 1 antibody
- IFG antibody
- IFI antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab27865 被引用在 1 文献中.
- McMahon M et al. Vaccination With Viral Vectors Expressing Chimeric Hemagglutinin, NP and M1 Antigens Protects Ferrets Against Influenza Virus Challenge. Front Immunol 10:2005 (2019). PubMed: 31497029