FITC荧光Anti-ICAM1抗体[1A29] (ab23835)
![Flow Cytometry - FITC Anti-ICAM1 antibody [1A29] (ab23835)](https://www.abcam.cn/ps/products/23/ab23835/Images/ab23835-33941-anti-icam1-antibody-1a29-fitc-flow-cytometry.gif "Flow Cytometry - FITC Anti-ICAM1 antibody [1A29] (ab23835)")
Key features and details
- FITC Mouse monoclonal [1A29] to ICAM1
- Suitable for: Flow Cyt
- Reacts with: Rat
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
Related conjugates and formulations
概述
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产品名称
FITC荧光Anti-ICAM1抗体[1A29]
参阅全部 ICAM1 一抗 -
描述
FITC荧光小鼠单克隆抗体[1A29] to ICAM1 -
宿主
Mouse -
偶联物
FITC. Ex: 493nm, Em: 528nm -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Rat -
免疫原
Tissue, cells or virus corresponding to Rat ICAM1. Rat Ax cell line (HEV derived cells).
Database link: Q00238 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.20
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
1A29 -
同种型
IgG1 -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab23835于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt | (1) |
| 说明 |
|---|
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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功能
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. -
序列相似性
Belongs to the immunoglobulin superfamily. ICAM family.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains. -
翻译后修饰
Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 25464 Rat
- SwissProt: Q00238 Rat
- Unigene: 12 Rat
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别名
- Antigen identified by monoclonal antibody BB2 antibody
- BB 2 antibody
- BB2 antibody
see all
图片
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Flow Cytometry - FITC Anti-ICAM1 antibody [1A29] (ab23835)ab23875 staining ICAM1 in stimulated rat spleen cells by Flow cytometry.
数据表及文件
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SDS download
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Datasheet download
文献 (5)
ab23835 被引用在 5 文献中.
- Orsi PR et al. A unique heterologous fibrin sealant (HFS) as a candidate biological scaffold for mesenchymal stem cells in osteoporotic rats. Stem Cell Res Ther 8:205 (2017). Flow Cyt ; Rat . PubMed: 28962655
- Tyrrell C et al. Differential alveolar epithelial injury and protein expression in pneumococcal pneumonia. Exp Lung Res 38:266-76 (2012). PubMed: 22563685
- Bell E et al. Dermal Stem Cells Can Differentiate Down an Endothelial Lineage. Stem Cells Dev : (2012). PubMed: 22571645
- Tamatani T et al. Molecular mechanisms underlying lymphocyte recirculation. II. Differential regulation of LFA-1 in the interaction between lymphocytes and high endothelial cells. Eur J Immunol 21:855-8 (1991). PubMed: 1672652
- Tamatani T & Miyasaka M Identification of monoclonal antibodies reactive with the rat homolog of ICAM-1, and evidence for a differential involvement of ICAM-1 in the adherence of resting versus activated lymphocytes to high endothelial cells. Int Immunol 2:165-71 (1990). PubMed: 2088483