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Immunology Adaptive Immunity B Cells CD

FITC荧光Anti-CD38抗体[90] (ab24978)

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Flow Cytometry - FITC Anti-CD38 antibody [90] (ab24978)

    Key features and details

    • FITC Rat monoclonal [90] to CD38
    • Suitable for: Flow Cyt
    • Reacts with: Mouse
    • Conjugation: FITC. Ex: 493nm, Em: 528nm
    • Isotype: IgG2a

    Conjugates logo Related conjugates and formulations

    APC PE PE/Cy5® Unconjugated

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    概述

    • 产品名称

      FITC荧光Anti-CD38抗体[90]
      参阅全部 CD38 一抗
    • 描述

      FITC荧光大鼠单克隆抗体[90] to CD38
    • 宿主

      Rat
    • 偶联物

      FITC. Ex: 493nm, Em: 528nm
    • 特异性

      ab24978 recognises CD38, an immunoregulatory ectoenzyme.
    • 经测试应用

      适用于: Flow Cytmore details
    • 种属反应性

      与反应: Mouse
    • 免疫原

      Tissue, cells or virus corresponding to Mouse CD38. Mouse bone marrow pre-B cells

    • 常规说明

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    性能

    • 形式

      Liquid
    • 存放说明

      Shipped at 4°C. Store at +4°C. Store In the Dark.
    • 存储溶液

      pH: 7.4
      Preservative: 0.1% Sodium azide
      Constituent: PBS
    • Concentration information loading...
    • 纯度

      Affinity purified
    • 克隆

      单克隆
    • 克隆编号

      90
    • 同种型

      IgG2a
    • 轻链类型

      kappa
    • 研究领域

      • Immunology
      • Adaptive Immunity
      • B Cells
      • CD
      • Stem Cells
      • Hematopoietic Progenitors
      • Hematopoietic Stem Cells
      • Human Lineage Negative
      • Stem Cells
      • Hematopoietic Progenitors
      • Surface Molecules
      • Microbiology
      • Organism
      • Virus
      • RNA Virus
      • ssRNA positive strand virus
      • SARS Coronavirus
      • Stem Cells
      • Hematopoietic Progenitors
      • Lymphoid
      • B Lymphocytic Lineage
      • Stem Cells
      • Hematopoietic Progenitors
      • Lymphoid
      • T Lymphocytic Lineage
      • Stem Cells
      • Hematopoietic Progenitors
      • Lymphoid
      • NK Cell Lineage
      • Stem Cells
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      • Myeloid
      • Monocytic Lineage
      • Immunology
      • Adaptive Immunity
      • Regulatory T Cells
      • Cancer
      • Cancer Metabolism
      • Response to hypoxia
      • Metabolism
      • Pathways and Processes
      • Metabolism processes
      • Hypoxia
      • Metabolism
      • Types of disease
      • Cancer

    相关产品

    • Alternative Versions

      • PE Anti-CD38 antibody [90] (ab23308)
      • APC Anti-CD38 antibody [90] (ab25041)
      • PE/Cy5® Anti-CD38 antibody [90] (ab25043)
      • Anti-CD38 antibody [90] (ab61400)
    • Isotype control

      • FITC Rat IgG2a, kappa monoclonal [RTK2758] - Isotype control (ab18446)

    应用

    The Abpromise guarantee

    Abpromise™承诺保证使用ab24978于以下的经测试应用

    “应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。

    应用 Ab评论 说明
    Flow Cyt
    说明
    应用说明
    Cellular activation [Induction of B lymphocyte proliferation]: Use at an assay dependent dilution.
    Flow Cyt: Use 1µg for 106 cells.
    IHC-Fr: Use at an assay dependent dilution.
    IP: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    靶标

    • 功能

      Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
    • 组织特异性

      Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.
    • 序列相似性

      Belongs to the ADP-ribosyl cyclase family.
    • 发展阶段

      Preferentially expressed at both early and late stages of the B and T-cell maturation. It is also detected on erythroid and myeloid progenitors in bone marrow, where the level of surface expression was shown to decrease during differentiation of blast-forming unit E to colony-forming unit E.
    • 细胞定位

      Membrane.
    • Target information above from: UniProt accession P28907 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • 数据库链接

      • Entrez Gene: 12494 Mouse
      • SwissProt: P56528 Mouse
      • Unigene: 249873 Mouse
      • 形式

        There are 2 isoforms produced by alternative splicing.
      • 别名

        • Acute lymphoblastic leukemia cells antigen CD38 antibody
        • ADP ribosyl cyclase 1 antibody
        • ADP ribosyl cyclase antibody
        • ADP ribosyl cyclase/cyclic ADP-ribose hydrolase antibody
        • ADP-ribosyl cyclase 1 antibody
        • ADPRC 1 antibody
        • ADPRC1 antibody
        • cADPr hydrolase 1 antibody
        • CD 38 antibody
        • CD38 antibody
        • CD38 antigen (p45) antibody
        • CD38 antigen antibody
        • CD38 molecule antibody
        • Cd38-rs1 antibody
        • CD38_HUMAN antibody
        • CD38H antibody
        • Cyclic ADP ribose hydrolase antibody
        • Cyclic ADP ribose hydrolase 1 antibody
        • Cyclic ADP-ribose hydrolase 1 antibody
        • EC 3.2.2.5 antibody
        • Ecto nicotinamide adenine dinucleotide glycohydrolase antibody
        • I-19 antibody
        • I19 (mouse) antibody
        • Lymphocyte differentiation antigen CD38 antibody
        • NAD(+) nucleosidase antibody
        • NIM-R5 antigen antibody
        • NIMR5 antigen (mouse) antibody
        • OTTHUMP00000158633 antibody
        • OTTHUMP00000217743 antibody
        • p45 antibody
        • T10 antibody
        see all

      图片

      • Flow Cytometry - FITC Anti-CD38 antibody [90] (ab24978)
        Flow Cytometry - FITC Anti-CD38 antibody [90] (ab24978)

        ab24978 staining mouse (BALB/c) spleen cells by flow cytometery. 1µg antibody was used for 106 cells.

      实验方案

      • Flow cytometry protocols
      • Immunohistochemistry protocols

      Click here to view the general protocols

      数据表及文件

      • SDS download

      • Datasheet download

        Download

      文献 (0)

      发表研究结果有使用 ab24978?请让我们知道,以便我们可以引用本数据表中的参考文章。

      ab24978 尚未被引用在任何文献中。

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