FITC荧光Anti-CD34抗体[581] (ab131589)
![Flow Cytometry - FITC Anti-CD34 antibody [581] (ab131589)](https://www.abcam.cn/ps/products/131/ab131589/Images/ab131589-1-anti-human-CD34-fitc-flow-cyt-human-peripheral-blood.jpg "Flow Cytometry - FITC Anti-CD34 antibody [581] (ab131589)")
Key features and details
- FITC Mouse monoclonal [581] to CD34
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
概述
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产品名称
FITC荧光Anti-CD34抗体[581]
参阅全部 CD34 一抗 -
描述
FITC荧光小鼠单克隆抗体[581] to CD34 -
宿主
Mouse -
偶联物
FITC. Ex: 493nm, Em: 528nm -
特异性
ab131589 recognizes the class III CD34 epitope resistant to neuraminidase, chymopapain and glycoprotease. -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human
不与反应: Sheep -
免疫原
The details of the immunogen for this antibody are not available.
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表位
An extracellular epitope of CD34. -
阳性对照
- Flow Cyt: Human blood cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: 0.2% BSA, 99% PBS -
Concentration information loading... -
纯度
Size exclusion -
克隆
单克隆 -
克隆编号
581 -
同种型
IgG1 -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab131589于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt |
Use at an assay dependent concentration.
4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. |
| 说明 |
|---|
|
Flow Cyt
Use at an assay dependent concentration. 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. |
靶标
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功能
Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. -
组织特异性
Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. -
序列相似性
Belongs to the CD34 family. -
发展阶段
On early hematopoietic progenitor cells. -
翻译后修饰
Highly glycosylated.
Phosphorylated on serine residues by PKC. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 947 Human
- Omim: 142230 Human
- SwissProt: P28906 Human
- Unigene: 374990 Human
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别名
- CD34 antibody
- CD34 antigen antibody
- CD34 molecule antibody
see all
图片
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Flow Cytometry - FITC Anti-CD34 antibody [581] (ab131589)Flow cytometry surface staining pattern of human peripheral whole blood labeling CD34 with ab131589 (4 µL reagent/100 µL of peripheral whole blood).
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![Flow Cytometry - FITC Anti-CD34 antibody [581] (ab131589)](https://www.abcam.cn/ps/products/131/ab131589/Images/ab131589-3-anti-cd34-fitc-antibody-flow-cyt-cd34-positive-stem-cells-human.jpg)
Flow Cytometry - FITC Anti-CD34 antibody [581] (ab131589)Flow cytometry analysis (surface staining) of human peripheral whole blood labeling CD34 with ab131589 (4 µL reagent/100 µL of peripheral whole blood). Histogram showing separation of human CD34 positive stem cells (red-filled) from lymphocytes (black-dashed). -
![Flow Cytometry - FITC Anti-CD34 antibody [581] (ab131589)](https://www.abcam.cn/ps/products/131/ab131589/Images/ab131589-2-anti-human-CD34-fitc-flow-cyt-human-peripheral-blood-2.jpg)
Flow Cytometry - FITC Anti-CD34 antibody [581] (ab131589)Flow cytometry surface staining pattern of human peripheral whole blood showing CD34 positive stem cells (red) stained using ab131589 (4 µL reagent/100 µL of peripheral whole blood).
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab131589 被引用在 2 文献中.
- Ma YS et al. Exosomal microRNA-15a from mesenchymal stem cells impedes hepatocellular carcinoma progression via downregulation of SALL4. Cell Death Discov 7:224 (2021). PubMed: 34455417
- Lv YJ et al. Low-dose cadmium exposure acts on rat mesenchymal stem cells via RANKL/OPG and downregulate osteogenic differentiation genes. Environ Pollut 249:620-628 (2019). PubMed: 30933759