FITC荧光Anti-CD226抗体[DX11] (ab33335)
Key features and details
- FITC Mouse monoclonal [DX11] to CD226
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
Related conjugates and formulations
概述
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产品名称
FITC荧光Anti-CD226抗体[DX11]
参阅全部 CD226 一抗 -
描述
FITC荧光小鼠单克隆抗体[DX11] to CD226 -
宿主
Mouse -
偶联物
FITC. Ex: 493nm, Em: 528nm -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human -
免疫原
Tissue, cells or virus corresponding to Human CD226. Human cytotoxic T lymphocyte clone.
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阳性对照
- Human peripheral blood lymphocytes.
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常规说明
Clone DX11 is reported to inhibit T and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen specific T cells.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.40
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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纯度
Protein G purified -
纯化说明
This antibody was purified from tissue culture supernatant. -
Primary antibody说明
Clone DX11 is reported to inhibit T and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen specific T cells. -
克隆
单克隆 -
克隆编号
DX11 -
骨髓瘤
Sp2/0 -
同种型
IgG1 -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab33335于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt |
1/10 - 1/20.
Use 10µl of the suggested working dilution to label 106 cells in 100µl.
ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
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说明 |
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Flow Cyt
1/10 - 1/20. Use 10µl of the suggested working dilution to label 106 cells in 100µl.
ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
|
靶标
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功能
Receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. -
组织特异性
Expressed by peripheral blood T-lymphocytes. -
序列相似性
Contains 2 Ig-like C2-type (immunoglobulin-like) domains. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 10666 Human
- Omim: 605397 Human
- SwissProt: Q15762 Human
- Unigene: 660130 Human
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别名
- adhesion glycoprotein antibody
- CD226 antibody
- CD226 antigen antibody
see all
图片
数据表及文件
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Datasheet download
文献 (1)
ab33335 被引用在 1 文献中.
- Kojima H et al. CD226 mediates platelet and megakaryocytic cell adhesion to vascular endothelial cells. J Biol Chem 278:36748-53 (2003). PubMed: 12847109