AB81468

Anti-Filaggrin 抗体

Name: Filaggrin抗体 (ab81468)| Abcam中文官网
Brand: Abcam Limited
SKU: AB81468
Price: 5062 CNY
Availability: InStock
Rating: 4 (9 reviews)

Anti-Filaggrin antibody

(9 Reviews)

(41 Publications)

Anti-Filaggrin antibody (ab81468) is a rabbit polyclonal antibody detecting Filaggrin in ICC/IF. Suitable for Human.

- Over 30 publications
- Trusted since 2009

查看别名

Filaggrin, FLG

1 Images

Immunocytochemistry/ Immunofluorescence - Anti-Filaggrin antibody (AB81468)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-Filaggrin antibody (AB81468)

ICC/IF image of ab81468 stained HeLa cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab81468, 1/1000 dilution) overnight at +4°C. The secondary antibody (green) was ab96899, DyLight® 488 goat anti-rabbit IgG (H+L) used at a 1/250 dilution for 1h.Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43μM.

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

反应种属

Human

应用

ICC/IF

applications

免疫原

Synthetic Peptide within Human FLG. The exact immunogen used to generate this antibody is proprietary information.

P20930

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }

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产品详情

What is this antibody validated in?
Anti-Filaggrin antibody (ab81468) is a rabbit polyclonal antibody and is validated for use in Immunocytochemistry/immunofluorescence (ICC/IF) in Human samples.

Trusted by the scientific community
Anti-Filaggrin (ab81468) was first used in a scientific publication in 2009 and has been cited over 30 times in peer-reviewed journals.

Reviewed by scientists
Anti-Filaggrin (ab81468) has over 5 independent reviews from customers.

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Protein A

存储溶液

Constituents: 2% Sucrose, 1.21% Tris, 0.75% Glycine

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis.

See full target information FLG

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文献 (41)

Recent publications for all applications. Explore the full list and refine your search

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 33:e70082 PubMed40880422

2025

Re-Epithelialisation in a Yorkshire Pig Full-Thickness Excisional Wound Model Is Associated With Keratinocyte Activation, Oxidative Stress, and Biomacromolecule Oxidation.

Applications

Unspecified application

Species

Unspecified reactive species

Dylan Tinney,John T Walker,Emily Truscott,Douglas W Hamilton

Frontiers in immunology 16:1503007 PubMed40491919

2025

Rab7 inhibitor enhances stem cell differentiation into keratinocyte-like cells with anti-inflammatory properties.

Applications

Unspecified application

Species

Unspecified reactive species

Raghad Alghazali,Mouna Tabebi,Moustafa Elmasry,Ahmed El-Serafi

Journal of ginseng research 49:326-330 PubMed40453350

2025

Compound K suppresses epidermal aging induced by IL-17A treatment and UVB irradiation.

Applications

Unspecified application

Species

Unspecified reactive species

A Young Kim,Ji-Yong Jung,Donghyun Kim,Jeong Hun Cho,Yong Deog Hong,Hyoung-June Kim,Si-Young Cho

Clinical, cosmetic and investigational dermatology 18:1151-1162 PubMed40356846

2025

-Derived Exosomes Enhance Skin Barrier Integrity by Upregulating Key Barrier-Related Proteins.

Applications

Unspecified application

Species

Unspecified reactive species

Yong-Han Cho,Ji-Woo Kim,Nari Kim,Hee-Sik Kim,Jun-Hwan Jang,Jun-Tae Bae,Wanil Kim

International journal of molecular sciences 26: PubMed40076477

2025

Bulge-Derived Epithelial Cells Isolated from Human Hair Follicles Using Enzymatic Digestion or Explants Result in Comparable Tissue-Engineered Skin.

Applications

Unspecified application

Species

Unspecified reactive species

Bettina Cattier,Rina Guignard,Israël Martel,Christian Martel,Carolyne Simard-Bisson,Danielle Larouche,Béatrice Guiraud,Sandrine Bessou-Touya,Lucie Germain

Scientific reports 13:22357 PubMed38102220

2023

β-endorphin suppresses ultraviolet B irradiation-induced epidermal barrier damage by regulating inflammation-dependent mTORC1 signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Hyung-Su Kim,Hyoung-June Kim,Yong-Deog Hong,Eui Dong Son,Si-Young Cho

Nature communications 14:7660 PubMed37996412

2023

Vector-borne Trypanosoma brucei parasites develop in artificial human skin and persist as skin tissue forms.

Applications

Unspecified application

Species

Unspecified reactive species

Christian Reuter,Laura Hauf,Fabian Imdahl,Rituparno Sen,Ehsan Vafadarnejad,Philipp Fey,Tamara Finger,Nicola G Jones,Heike Walles,Lars Barquist,Antoine-Emmanuel Saliba,Florian Groeber-Becker,Markus Engstler

Frontiers in immunology 14:1273182 PubMed38053996

2023

Epidermal keratinocyte-specific STAT3 deficiency aggravated atopic dermatitis-like skin inflammation in mice through TSLP upregulation.

Applications

Unspecified application

Species

Unspecified reactive species

Zhao-Yuan Wang,Yu-Xin Zheng,Fan Xu,Ying-Zhe Cui,Xue-Yan Chen,Si-Qi Chen,Bing-Xi Yan,Yuan Zhou,Min Zheng,Xiao-Yong Man

International journal of molecular sciences 24: PubMed38003573

2023

Lipids Reduce Cytokine-Induced Pro-Inflammatory Signalling and Barrier Dysfunction in Human Keratinocyte Models.

Applications

Unspecified application

Species

Unspecified reactive species

Jamie M L Kok,Georgina C Dowd,Jaydee D Cabral,Lyn M Wise

Journal of nanobiotechnology 21:354 PubMed37775761

2023

Bioinspired polydopamine nanoparticles as efficient antioxidative and anti-inflammatory enhancers against UV-induced skin damage.

Applications

Unspecified application

Species

Unspecified reactive species

Jia Zhang,Yuqi Zhou,Zhaoting Jiang,Chenhui He,Bo Wang,Qi Wang,Zeqian Wang,Tong Wu,Xiaoqi Chen,Ziwei Deng,Chunying Li,Zhe Jian

View all publications

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Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。

详情请参阅我们的条款与条件。

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For licensing inquiries, please contact partnerships@abcam.com

Anti-Filaggrin 抗体

Anti-Filaggrin antibody

Immunocytochemistry/ Immunofluorescence - Anti-Filaggrin antibody (AB81468)