重组Anti-FGFR1 Oncogene Partner抗体[EPR9929] (ab156013)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR9929] to FGFR1 Oncogene Partner
- Suitable for: WB, ICC/IF
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-FGFR1 Oncogene Partner抗体[EPR9929]
参阅全部 FGFR1 Oncogene Partner 一抗 -
描述
兔单克隆抗体[EPR9929] to FGFR1 Oncogene Partner -
宿主
Rabbit -
经测试应用
适用于: WB, ICC/IFmore details
不适用于: IHC-P -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- HeLa, 293T and Saos-2 cell lysates; HeLa cells.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20ºC. -
存储溶液
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR9929 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab156013于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/1000 - 1/10000. Predicted molecular weight: 43 kDa.
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ICC/IF |
1/100 - 1/250.
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说明 |
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WB
1/1000 - 1/10000. Predicted molecular weight: 43 kDa. |
ICC/IF
1/100 - 1/250. |
靶标
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功能
Required for anchoring microtubules to the centrosomes. -
组织特异性
Ubiquitous. Highly expressed in heart, liver, muscle, kidney, intestine, colon, adrenal gland, prostate, testis, and pancreas. -
疾病相关
Note=A chromosomal aberration involving FGFR1OP may be a cause of stem cell myeloproliferative disorder (MPD). Translocation t(6;8)(q27;p11) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion proteins FGFR1OP-FGFR1 or FGFR1-FGFR1OP may exhibit constitutive kinase activity and be responsible for the transforming activity. -
序列相似性
Belongs to the FGFR1OP family.
Contains 1 LisH domain. -
细胞定位
Cytoplasm > cytoskeleton > centrosome. Associated with gamma-tubulin. - Information by UniProt
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数据库链接
- Entrez Gene: 11116 Human
- Entrez Gene: 75296 Mouse
- Entrez Gene: 365103 Rat
- Entrez Gene: 683722 Rat
- Omim: 605392 Human
- SwissProt: O95684 Human
- SwissProt: Q66JX5 Mouse
- SwissProt: Q4V7C1 Rat
see all -
别名
- FGFR1 oncogene partner antibody
- FGFR1OP antibody
- Fibroblast growth factor receptor 1 oncogene partner antibody
see all
图片
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All lanes : Anti-FGFR1 Oncogene Partner antibody [EPR9929] (ab156013) at 1/1000 dilution
Lane 1 : HeLa cell lysate
Lane 2 : 293T cell lysate
Lane 3 : Saos-2 cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 43 kDa -
Immunofluorescent analysis of HeLa cells labeling FGFR1 Oncogene Partner with ab156013 at 1/100 dilution.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab156013 被引用在 1 文献中.
- Jiang H et al. FOP Negatively Regulates Ciliogenesis and Promotes Cell Cycle Re-entry by Facilitating Primary Cilia Disassembly. Front Cell Dev Biol 8:590449 (2020). PubMed: 33304902