Anti-Fetal Hemoglobin抗体(ab19363)
Key features and details
- Sheep polyclonal to fetal hemoglobin
- Suitable for: Immunoelectrophoresis, Double Immunodiffusion
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-Fetal Hemoglobin抗体
参阅全部 fetal hemoglobin 一抗 -
描述
羊多克隆抗体to fetal hemoglobin -
宿主
Sheep -
特异性
By immunoelectrophoresis, the antiserum reacts specifically with human fetal hemoglobin. No antibody was detected against hemoglobin A1, A2, S or human serum proteins
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经测试应用
适用于: Immunoelectrophoresis, Double Immunodiffusionmore details -
种属反应性
与反应: Human -
免疫原
Full length protein corresponding to Human Hemoglobin. Sheep were immunized with purified human hemoglobin F of fetal red blood cell origin.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 6.8
Preservative: 0.1% Sodium azide
Constituents: 1.21% Tris, 0.02% Sodium chloride -
Concentration information loading... -
纯度
IgG fraction -
纯化说明
Antiserum was solid phase adsorbed against hemoglobin A to ensure specificity. The antiserum was fractionated and passed over DEAE to yield an IgG fraction. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab19363于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Immunoelectrophoresis |
Use at an assay dependent concentration.
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| Double Immunodiffusion |
Use at an assay dependent concentration.
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| 说明 |
|---|
|
Immunoelectrophoresis
Use at an assay dependent concentration. |
|
Double Immunodiffusion
Use at an assay dependent concentration. |
靶标
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相关性
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3' -
细胞定位
Cytoplasmic -
数据库链接
- Entrez Gene: 3047 Human
- Entrez Gene: 3048 Human
- Omim: 142200 Human
- Omim: 142250 Human
- SwissProt: P69891 Human
- SwissProt: P69892 Human
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别名
- A gamma globin antibody
- G gamma globin antibody
- Gamma 1 globin antibody
see all
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab19363 尚未被引用在任何文献中。