AB204310

Anti-Ferredoxin Reductase 抗体

Name: Ferredoxin Reductase抗体 (ab204310)| Abcam中文官网
Brand: Abcam Limited
SKU: AB204310
Price: 4560 CNY
Availability: InStock

Anti-Ferredoxin Reductase antibody

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(6 Publications)

Rabbit Polyclonal Ferredoxin Reductase antibody. Suitable for IHC-P, ICC, WB and reacts with Human samples. Cited in 6 publications. Immunogen corresponding to Recombinant Fragment Protein within Human FDXR aa 1-150.

查看别名

ADXR, FDXR, AR, Adrenodoxin reductase, Ferredoxin--NADP(+) reductase, Ferredoxin reductase

6 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ferredoxin Reductase antibody (AB204310)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ferredoxin Reductase antibody (AB204310)

Paraffin embedded human testis tissue stained for Ferredoxin Reductase using ab204310 at 1/500 dilution in immunohistochemical analysis.

Heat mediated antigen retrieval was performed with citrate buffer pH 6 before the IHC staining protocol.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ferredoxin Reductase antibody (AB204310)

Paraffin embedded human liver tissue stained for Ferredoxin Reductase using ab204310 at 1/500 dilution in immunohistochemical analysis. Shows no positivity in hepatocytes cells as expected.

Heat mediated antigen retrieval was performed with citrate buffer pH 6 before the IHC staining protocol.

Supplier Data

Immunocytochemistry - Anti-Ferredoxin Reductase antibody (AB204310)

Immunocytochemistry analysis of U-2 OS cells (PFA-fixed/Triton X-100 permeabilized) labeling Ferredoxin Reductase with ab204310 at 2 μg/mL.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ferredoxin Reductase antibody (AB204310)

Paraffin embedded human adrenal gland tissue stained for Ferredoxin Reductase using ab204310 at 1/500 dilution in immunohistochemical analysis.

Heat mediated antigen retrieval was performed with citrate buffer pH 6 before the IHC staining protocol.

Supplier Data

Western blot - Anti-Ferredoxin Reductase antibody (AB204310)

All lanes:

Western blot - Anti-Ferredoxin Reductase antibody (ab204310) at 0.4 µg/mL

Lane 1:

RT4 (human urinary bladder cancer cell line) cell lysate

Lane 2:

U-251 MG (formally U-373 MG) (human brain glioma cell line) cell lysate

Predicted band size: 54 kDa

false

Supplier Data

Western blot - Anti-Ferredoxin Reductase antibody (AB204310)

All lanes:

Western blot - Anti-Ferredoxin Reductase antibody (ab204310) at 0.4 µg/mL

Lane 1:

A549 (human lung carcinoma cell line) cell lysate

Lane 2:

U-251 MG (formally U-373 MG) (human brain glioma cell line) cell lysate

Predicted band size: 54 kDa

false

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

反应种属

Human

应用

ICC, WB, IHC-P

applications

免疫原

Recombinant Fragment Protein within Human FDXR aa 1-150. The exact immunogen used to generate this antibody is proprietary information.

P22570

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICC" : {"fullname" : "Immunocytochemistry", "shortname":"ICC"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": " Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICC-species-checked": "testedAndGuaranteed", "ICC-species-dilution-info": "0.25-2 µg/mL", "ICC-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "" } } }

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Immunogen

存储溶液

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.

See full target information FDXR

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文献 (6)

Recent publications for all applications. Explore the full list and refine your search

Clinical and experimental otorhinolaryngology 17:206-216 PubMed39104018

2024

Novel Variant of FDXR as a Molecular Etiology of Postlingual Post-synaptic Auditory Neuropathy Spectrum Disorder via Mitochondrial Dysfunction: Reiteration of the Correlation between Genotype and Cochlear Implantation Outcomes.

Applications

Unspecified application

Species

Unspecified reactive species

Bong Jik Kim,Yujin Kim,Ju Ang Kim,Jin Hee Han,Min Young Kim,Hee Kyung Yang,Chae-Seo Rhee,Young Cheol Kang,Chun-Hyung Kim,Byung Yoon Choi

Genetics in medicine open 2:100841 PubMed39669623

2023

Clinical study of ferredoxin-reductase-related mitochondriopathy: Genotype-phenotype correlation and proposal of ancestry-based carrier screening in the Mexican population.

Applications

Unspecified application

Species

Unspecified reactive species

Teresa Campbell,Jesse Slone,Hallie Metzger,Wensheng Liu,Stephanie Sacharow,Amy Yang,Mariya Moosajee,Chiara La Morgia,Valerio Carelli,Flavia Palombo,Matthew A Lines,A Micheil Innes,Rebecca J Levy,Derek Neilson,Nicola Longo,Taosheng Huang

Molecular therapy. Methods & clinical development 18:84-97 PubMed32995353

2020

Systemic Delivery of AAV- Mitigates the Phenotypes of Mitochondrial Disorders in Mutant Mice.

Applications

Unspecified application

Species

Unspecified reactive species

Li Yang,Jesse Slone,Weiwei Zou,Luis F Queme,Michael P Jankowski,Fei Yin,Taosheng Huang

Nutrients 11: PubMed31500291

2019

Distinct TP53 Mutation Subtypes Differentially Influence Cellular Iron Metabolism.

Applications

Unspecified application

Species

Unspecified reactive species

Stephen L Clarke,Laurie R Thompson,Eshan Dandekar,Aishwarya Srinivasan,McKale R Montgomery

Human molecular genetics 27:2224 PubMed29554255

2018

Biallelic mutations in the ferredoxin reductase gene cause novel mitochondriopathy with optic atrophy.

Applications

Unspecified application

Species

Unspecified reactive species

Yanyan Peng,Deepali N Shinde,C Alexander Valencia,Jun-Song Mo,Jill Rosenfeld,Megan Truitt Cho,Adam Chamberlin,Zhuo Li,Jie Liu,Baoheng Gui

Human molecular genetics 26:4937-4950 PubMed29040572

2017

Biallelic mutations in the ferredoxin reductase gene cause novel mitochondriopathy with optic atrophy.

Applications

Unspecified application

Species

Unspecified reactive species

Yanyan Peng,Deepali N Shinde,C Alexander Valencia,Jun-Song Mo,Jill Rosenfeld,Megan Truitt Cho,Adam Chamberlin,Zhuo Li,Jie Liu,Baoheng Gui,Rachel Brockhage,Alice Basinger,Brenda Alvarez-Leon,Peter Heydemann,Pilar L Magoulas,Andrea M Lewis,Fernando Scaglia,Solange Gril,Shuk Ching Chong,Matthew Bower,Kristin G Monaghan,Rebecca Willaert,Maria-Renee Plona,Rich Dineen,Francisca Milan,George Hoganson,Zoe Powis,Katherine L Helbig,Jennifer Keller-Ramey,Belinda Harris,Laura C Anderson,Torrian Green,Stacey J Sukoff Rizzo,Julie Kaylor,Jiani Chen,Min-Xin Guan,Elizabeth Sellars,Steven P Sparagana,James B Gibson,Laura G Reinholdt,Sha Tang,Taosheng Huang

View all publications

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Anti-Ferredoxin Reductase 抗体

Anti-Ferredoxin Reductase antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ferredoxin Reductase antibody (AB204310)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ferredoxin Reductase antibody (AB204310)

Immunocytochemistry - Anti-Ferredoxin Reductase antibody (AB204310)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ferredoxin Reductase antibody (AB204310)

Western blot - Anti-Ferredoxin Reductase antibody (AB204310)

Western blot - Anti-Ferredoxin Reductase antibody (AB204310)