Anti-FAM3C/ILEI抗体(ab56065)
Key features and details
- Rabbit polyclonal to FAM3C/ILEI
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-FAM3C/ILEI抗体
参阅全部 FAM3C/ILEI 一抗 -
描述
兔多克隆抗体to FAM3C/ILEI -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse
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免疫原
Synthetic peptide corresponding to Mouse FAM3C/ILEI (N terminal).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab56065于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 25 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
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| 说明 |
|---|
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 25 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein. |
靶标
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功能
May be involved in retinal laminar formation. Promotes epithelial to mesenchymal transition. -
组织特异性
Present in most secretory epithelia (at protein level). -
序列相似性
Belongs to the FAM3 family. -
细胞定位
Secreted. Cytoplasmic vesicle. Cytoplasmic in some cancer cells. - Information by UniProt
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数据库链接
- Entrez Gene: 10447 Human
- Entrez Gene: 27999 Mouse
- Omim: 608618 Human
- SwissProt: Q92520 Human
- SwissProt: Q91VU0 Mouse
- Unigene: 272375 Human
- Unigene: 434053 Human
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别名
- Fam3c antibody
- FAM3C_HUMAN antibody
- Family with sequence similarity 3 member C antibody
see all
图片
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Western blot - Anti-FAM3C/ILEI antibody (ab56065)Anti-FAM3C/ILEI antibody (ab56065) at 1 µg/ml + Human liver tissue lysate - total protein at 10 µg
Secondary
Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Predicted band size: 25 kDa
Observed band size: 30 kDa why is the actual band size different from the predicted?
Additional bands at: 46 kDa. We are unsure as to the identity of these extra bands.
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab56065 被引用在 3 文献中.
- Pan R et al. Significant effects of Ganoderma lucidum polysaccharide on lipid metabolism in diabetes may be associated with the activation of the FAM3C-HSF1-CAM signaling pathway. Exp Ther Med 22:820 (2021). PubMed: 34131443
- Xia HG et al. Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death. J Cell Biol 210:705-16 (2015). PubMed: 26323688
- Chaudhury A et al. TGF-beta-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI. Nat Cell Biol : (2010). PubMed: 20154680