Anti-FAM172A抗体(ab121364)
Key features and details
- Rabbit polyclonal to FAM172A
- Suitable for: ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-FAM172A抗体 -
描述
兔多克隆抗体to FAM172A -
宿主
Rabbit -
经测试应用
适用于: ICC/IFmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat
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免疫原
Recombinant fragment within Human FAM172A aa 1-150. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: Q8WUF8 -
阳性对照
- ICC/IF: U-251 MG cells;
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab121364于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
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| 说明 |
|---|
|
ICC/IF
Use a concentration of 0.25 - 2 µg/ml. |
靶标
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序列相似性
Belongs to the UPF0528 family. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 83989 Human
- Entrez Gene: 68675 Mouse
- Entrez Gene: 294606 Rat
- SwissProt: Q8WUF8 Human
- SwissProt: Q3TNH5 Mouse
- Unigene: 600086 Human
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别名
- C5orf21 antibody
- F172A_HUMAN antibody
- fam172a antibody
see all
图片
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Immunocytochemistry/ Immunofluorescence - Anti-FAM172A antibody (ab121364)
Immunocytochemistry analysis of U-251 MG (human brain glioma cell line) cells labelling FAM172A with ab121364 at 2 µg/mL.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (8)
ab121364 被引用在 8 文献中.
- Sallis S et al. The CHARGE syndrome-associated protein FAM172A controls AGO2 nuclear import. Life Sci Alliance 6:N/A (2023). PubMed: 37221016
- Bélanger C et al. CHARGE syndrome-associated proteins FAM172A and CHD7 influence male sex determination and differentiation through transcriptional and alternative splicing mechanisms. FASEB J 36:e22176 (2022). PubMed: 35129866
- Chen Y et al. FAM172A inhibits EMT in pancreatic cancer via ERK-MAPK signaling. Biol Open 9:N/A (2020). PubMed: 31988090
- Xiao F et al. FAM172A Deletion May Enhance Hepatic Steatosis by Promoting ER Stress. Dig Dis Sci N/A:N/A (2020). PubMed: 32945983
- Xu AM et al. FAM172A affects cell proliferation and apoptosis not by targeting β-tubulin in HepG2 cells. Transl Cancer Res 9:5637-5644 (2020). PubMed: 35117927
- Liu W et al. Expression of family with sequence similarity 172 member A and nucleotide-binding protein 1 is associated with the poor prognosis of colorectal carcinoma. Oncol Lett 14:3587-3593 (2017). PubMed: 28927116
- Liu W et al. miR-27a promotes proliferation, migration, and invasion of colorectal cancer by targeting FAM172A and acts as a diagnostic and prognostic biomarker. Oncol Rep 37:3554-3564 (2017). PubMed: 28440497
- Li MF et al. FAM172A protein promotes the proliferation of human papillary thyroid carcinoma cells via the p38 mitogen-activated protein kinase pathway. Mol Med Rep 13:353-8 (2016). PubMed: 26573560