Anti-FAM120A/OSSA抗体(ab106454)
Key features and details
- Rabbit polyclonal to FAM120A/OSSA
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-FAM120A/OSSA抗体
参阅全部 FAM120A/OSSA 一抗 -
描述
兔多克隆抗体to FAM120A/OSSA -
宿主
Rabbit -
特异性
ab106454 will not cross-react with FAM120B / PGCC1. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human FAM120A/OSSA (internal sequence).
Database link: NP_055427 -
阳性对照
- SK-N-SH cell lysate
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab106454于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 122 kDa.
|
| 说明 |
|---|
|
WB
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 122 kDa. |
靶标
-
功能
May participate in mRNA transport in the cytoplasm (By similarity). Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses. -
组织特异性
Ubiquitously expressed. Highly expressed in scirrhous-type gastric cancer tissues compared with normal gastric mucosa (at protein level). -
序列相似性
Belongs to the constitutive coactivator of PPAR-gamma family. -
翻译后修饰
Arg-982 is dimethylated, probably to asymmetric dimethylarginine.
Phosphorylated on tyrosine by src family kinases upon ultraviolet exposure. -
细胞定位
Cytoplasm. Cell membrane. Translocates to plasma membrane upon ultraviolet exposure. - Information by UniProt
-
数据库链接
- Entrez Gene: 23196 Human
- GenBank: NP_055427.2 Human
- Omim: 612265 Human
- SwissProt: Q9NZB2 Human
- Unigene: 372003 Human
- Unigene: 707324 Human
-
别名
- C9orf10 antibody
- Chromosome 9 open reading frame 10 antibody
- Constitutive coactivator of PPAR gamma like protein 1 antibody
see all
图片
-
Western blot - Anti-FAM120A/OSSA antibody (ab106454)Lane 1 : Anti-FAM120A/OSSA antibody (ab106454) at 0.5 µg/ml
Lane 2 : Anti-FAM120A/OSSA antibody (ab106454) at 1 µg/ml
All lanes : SK-N-SH cell lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 122 kDa
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (1)
ab106454 被引用在 1 文献中.
- Zheng G et al. TMEM43-S358L mutation enhances NF-?B-TGFß signal cascade in arrhythmogenic right ventricular dysplasia/cardiomyopathy. Protein Cell N/A:N/A (2018). PubMed: 29980933