Anti-Factor D/CFD抗体[D10/4] (ab121054)
Key features and details
- Mouse monoclonal [D10/4] to Factor D/CFD
- Suitable for: WB, Sandwich ELISA
- Reacts with: Human
- Isotype: IgG2a
概述
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产品名称
Anti-Factor D/CFD抗体[D10/4]
参阅全部 Factor D/CFD 一抗 -
描述
小鼠单克隆抗体[D10/4] to Factor D/CFD -
宿主
Mouse -
特异性
ab121054 is specific for complement Factor D/CFD in Human serum and plasma.
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经测试应用
适用于: WB, Sandwich ELISAmore details -
种属反应性
与反应: Human -
免疫原
Full length protein corresponding to Human Factor D/CFD.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.1% Sodium azide
Constituents: 97% Phosphate Buffer, 2.9% Sodium chloride -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
D10/4 -
骨髓瘤
x63-Ag8.653 -
同种型
IgG2a -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab121054于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use at an assay dependent concentration.
|
|
| Sandwich ELISA |
Use at an assay dependent concentration.
as capture antibody. The dilution guideline for ELISA is based on sandwich ELISA in combination with a polyclonal antibody against the antigen. |
| 说明 |
|---|
|
WB
Use at an assay dependent concentration. |
|
Sandwich ELISA
Use at an assay dependent concentration. as capture antibody. The dilution guideline for ELISA is based on sandwich ELISA in combination with a polyclonal antibody against the antigen. |
靶标
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功能
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. -
疾病相关
Defects in CFD are the cause of complement factor D deficiency (CFD deficiency) [MIM:134350]. CFD deficiency predisposes to invasive meningococcal disease. -
序列相似性
Belongs to the peptidase S1 family.
Contains 1 peptidase S1 domain. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 1675 Human
- Omim: 134350 Human
- SwissProt: P00746 Human
- Unigene: 155597 Human
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别名
- Adipsin antibody
- Adipsin/complement factor D antibody
- Adn antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab121054 尚未被引用在任何文献中。