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Anti-ETS1 (phospho T38)抗体(ab59179)

Reviews (1)Q&A (2)References (11)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ETS1 (phospho T38) antibody (ab59179)

    Key features and details

    • Rabbit polyclonal to ETS1 (phospho T38)
    • Suitable for: IHC-P
    • Reacts with: Human
    • Isotype: IgG

    概述

    • 产品名称

      Anti-ETS1 (phospho T38)抗体
      参阅全部 ETS1 一抗

    • 描述

      兔多克隆抗体to ETS1 (phospho T38)

    • 宿主

      Rabbit

    • 经测试应用

      适用于: IHC-Pmore details

    • 种属反应性

      与反应: Human

    • 免疫原

      Synthetic peptide corresponding to Human ETS1 aa 1-100 (phospho T38).
      Database link: P14921

    • 常规说明

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    性能

    应用

    The Abpromise guarantee

    Abpromise™承诺保证使用ab59179于以下的经测试应用

    “应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

    应用 Ab评论 说明
    IHC-P
    Use at an assay dependent concentration.
    说明
    IHC-P
    Use at an assay dependent concentration.

    靶标

    • 功能

      Transcription factor.

    • 序列相似性

      Belongs to the ETS family.
      Contains 1 ETS DNA-binding domain.
      Contains 1 PNT (pointed) domain.

    • 翻译后修饰

      Sumoylated on Lys-15 and Lys-227, preferentially by SUMO2; which inhibits transcriptional activity.
      Ubiquitinated; which induces proteasomal degradation.

    • 细胞定位

      Nucleus.
    • Information by UniProt

    • 数据库链接

      • 别名

        • Avian erythroblastosis virus E26 (v ets) oncogene homolog 1 antibody
        • C ets 1 protein antibody
        • c-ets-1 antibody
        • ETS 1 antibody
        • Ets protein antibody
        • ETS proto-oncogene 1, transcription factor antibody
        • ETS1 antibody
        • ETS1 oncogene antibody
        • ETS1 protein antibody
        • ETS1_HUMAN antibody
        • EWSR 2 antibody
        • EWSR2 antibody
        • FLJ10768 antibody
        • Oncogene ETS1 antibody
        • P54 antibody
        • Protein C-ets-1 antibody
        • v ets avian erythroblastosis virus E2 oncogene homolog antibody
        • v ets avian erythroblastosis virus E2 oncogene homolog 1 antibody
        • v ets avian erythroblastosis virus E26 oncogene homolog 1 antibody
        • v ets erythroblastosis virus E26 oncogene homolog 1 antibody
        • v-ets erythroblastosis virus E26 oncogene homolog 1 antibody
        see all

      图片

      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ETS1 (phospho T38) antibody (ab59179)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ETS1 (phospho T38) antibody (ab59179)
        Immunohistochemical analysis of paraffin embedded human breast carcinoma tissue using ab59179 at 1/50 dilution. Left: untreated. Right: sample treated with immunising peptide.

      文献 (11)

      发表研究结果有使用 ab59179？请让我们知道，以便我们可以引用本数据表中的参考文章。

      ab59179 被引用在 11 文献中.

      • Sheng K  et al. Transcriptional Regulation of Siglec-15 by ETS-1 and ETS-2 in Hepatocellular Carcinoma Cells. Int J Mol Sci 24:N/A (2023). PubMed: 36614238
      • Ichikawa MK  et al. Ets family proteins regulate the EMT transcription factors Snail and ZEB in cancer cells. FEBS Open Bio 12:1353-1364 (2022). PubMed: 35451213
      • Xiao GY & Schmid SL FCHSD2 controls oncogenic ERK1/2 signaling outcome by regulating endocytic trafficking. PLoS Biol 18:e3000778 (2020). PubMed: 32678845
      • Priebe V  et al. Role of ETS1 in the Transcriptional Network of Diffuse Large B Cell Lymphoma of the Activated B Cell-Like Type. Cancers (Basel) 12:N/A (2020). PubMed: 32679859
      • Yang Z  et al. Regulation of cisplatin-resistant head and neck squamous cell carcinoma by the SRC/ETS-1 signaling pathway. BMC Cancer 19:485 (2019). PubMed: 31118072
      View all Publications for this product

      客户评价及客户问答

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      1-3 of 3 Abreviews or Q&A

      Western blot abreview for Anti-ETS1 (phospho T38) antibody

       Below Average
      Abreviews
      abreview image
      Application
      Western blot
      Loading amount
      50 µg
      Gel Running Conditions
      Reduced Denaturing (4-12% SDS-PAGE)
      Sample
      Human Cell lysate - whole cell (A2058 and A375)
      Specification
      A2058 and A375
      Blocking step
      Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
      Read More
      The reviewer received a reward from Abcam’s Loyalty Program in thanks for submitting this Abreview and for helping the scientific community make better-informed decisions.

      Abcam user community

      Verified customer

      提交于 Dec 16 2013

      Question

      Hi Abcam,

      A customer has the following enquiry regarding this antibody;

      I also notice that this product is not listed for use with Western blotting.

      Could you please clarify if you have had people using it for western blotting or if at all it is suitable for this.

      Can you please help? Thanks J

      Kind regards,

      Read More
      Answer

      Thank you for your enquiry.

      I am sorry to confirm that as far as we are aware, ab59179 has never been tested in Western blot. All tested applications covered by the 6 month guarantee are specified on our datasheets, and these are updated as soon as any new information is brought to our attention.

      If the customer would like to test ab59179 in WB, please do not hesitate to contact me again prior to the purchase by replying to this message as you may be eligible for our AbTrial testing discount program.

      Otherwise, we like to encourage all of our customers to submit an Abreview via the online product datasheet. We always appreciate customer feedback, whether positive or negative, and we make all product information available to researchers. Plus, each Abreview earns Abpoints that can be used for discounts on future purchases or rewards such as Amazon.com gift certificates.

      To find out more about our Abreview system, please see the following link:

      https://www.abcam.com/abreviews

      I hope this information is helpful. Please do not hesitate to contact me for any further advice or information.

      Read More

      Question

      Would like to try this antibody in Western blot.

      Read More
      Answer

      Thank you for your call today. Please see below for information about your testing discount code, and let me know if you have any questions.

      DISCOUNT CODE: ***
      Expiration date: September 24, 2012

      This code will give you 1 free primary antibody. To redeem this offer, please submit an Abreview for ab59179 in WB and include this code in the “Additional Comments” section so we know the Abreview is for this promotion. Please remember that submission of the Abreview is sufficient for the discount code to become active. For more information on how to submit an Abreview, please visit the site: www.abcam.com/Abreviews.

      The code will be active once the Abreview has been submitted and can be redeemed in one of the following ways: 1) Call to place your order and mention the code to our customer service department; 2) Include the code in your fax order; 3) Place your order on the web and enter the promotional code.

      Any feedback that you can provide will be greatly appreciated, whether positive or negative. If you have any further questions, please do not hesitate to contact us. We look forward to receiving your Abreview and wish you luck with your research.

      The terms and conditions applicable to this offer can be found here: www.abcam.com/collaborationdiscount.

      Read More

      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
      For licensing inquiries, please contact partnerships@abcam.com