Anti-ESAT6抗体(ab45073)
Key features and details
- Rabbit polyclonal to ESAT6
- Suitable for: WB
- Reacts with: Mycobacterium bovis
- Isotype: IgG
概述
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产品名称
Anti-ESAT6抗体 -
描述
兔多克隆抗体to ESAT6 -
宿主
Rabbit -
特异性
The rabbit polyclonal antibody to EsaT-6 recognizes the EsaT-6 (Rv3875) protein of Mycobacterium tuberculosis and Mycobacterium bovis.
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经测试应用
适用于: WBmore details -
种属反应性
与反应: Mycobacterium bovis, Mycobacterium tuberculosis -
免疫原
Recombinant full length protein corresponding to ESAT6.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.40
Preservative: 0.097% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab45073于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB | (2) |
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 11 kDa.
Use under reducing conditions. |
说明 |
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WB
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 11 kDa. Use under reducing conditions. |
靶标
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相关性
The ESAT6 antigen from Mycobacterium tuberculosis is a dominant target for cell mediated immunity in the early phase of tuberculosis (TB) in TB patients as well as in various animal models. ESAT6 is not found in M. bovis BCG. Its function is not known but it elicits high level of IFN-gamma from memory effector cells during the first phase of a protective immune response. -
细胞定位
Secreted -
别名
- 6 kDa early secretory antigenic target antibody
- 6 kDa early secretory antigenic target ESXA antibody
- ESAT 6 antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab45073 被引用在 4 文献中.
- Yang H et al. Interception of host fatty acid metabolism by mycobacteria under hypoxia to suppress anti-TB immunity. Cell Discov 7:90 (2021). PubMed: 34608123
- Sepulveda D et al. Bioelectrochemical Detection of Mycobacterium tuberculosis ESAT-6 in an Antibody-Based Biomicrosystem. Sensors (Basel) 17:N/A (2017). PubMed: 28937645
- Tan K et al. Comparison of BCG prime-DNA booster and rBCG regimens for protection against tuberculosis. Hum Vaccin Immunother 10:391-8 (2014). PubMed: 24192709
- Nguyen YH et al. Rapid identification and drug susceptibility screening of ESAT-6 secreting Mycobacteria by a NanoELIwell assay. Sci Rep 2:635 (2012). Functional Studies . PubMed: 22957139