Anti-epithelial Sodium Channel alpha抗体
Anti-epithelial Sodium Channel alpha antibody
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(4 Publications)
Rabbit Polyclonal epithelial Sodium Channel alpha antibody. Suitable for WB and reacts with Mouse, Rat samples. Cited in 4 publications. Immunogen corresponding to Synthetic Peptide within Human SCNN1A aa 200-250 conjugated to Keyhole Limpet Haemocyanin.
查看别名
SCNN1, SCNN1A, Amiloride-sensitive sodium channel subunit alpha, Alpha-NaCH, Epithelial Na(+) channel subunit alpha, Nonvoltage-gated sodium channel 1 subunit alpha, SCNEA, Alpha-ENaC, ENaCA
- WB
Supplier Data
Western blot - Anti-epithelial Sodium Channel alpha antibody (AB214192)
Rat kidney lysate (40 ug)
Primary : ab214192 at 1/1000 dilution
Secondary : IRDye800CW Goat anti-Rabbit IgG at 1/20000 dilution
Predicted band size : 76 kD
Observed band size : 77 kD
All lanes:
Western blot - Anti-epithelial Sodium Channel alpha antibody (ab214192)
Predicted band size: 75 kDa
false
- WB
Supplier Data
Western blot - Anti-epithelial Sodium Channel alpha antibody (AB214192)
Mouse kidney lysate (40 ug)
Primary : ab214192 at 1/1000 dilution
Secondary : IRDye800CW Goat anti-Rabbit IgG at 1/20000 dilution
Predicted band size : 76 kD
Observed band size : 77 kD
All lanes:
Western blot - Anti-epithelial Sodium Channel alpha antibody (ab214192)
Predicted band size: 75 kDa
false
反应性数据
性能和储存信息
形式
纯化工艺
存储溶液
运输条件
推荐的短期储存时间
推荐的短期储存条件
推荐的长期储存条件
分装信息
储存信息
补充信息
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The epithelial sodium channel alpha facilitates sodium ion entry into cells which impacts fluid balance blood pressure and extracellular fluid volume. The alpha subunit functions as part of a heterotrimeric complex consisting of alpha beta and gamma subunits forming the complete active channel. The coordinated action of these subunits ensures regulated ion transport which is essential for maintaining homeostasis in epithelial tissues.
Pathways
ENaC channels participate in the renin-angiotensin-aldosterone system and are involved in sodium reabsorption processes. This channel works closely with proteins like aldosterone to modulate its activity in response to changes in body fluid status. ENaC's ability to regulate sodium flux links it to key physiological functions in fluid and electrolyte balance pathways.
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靶点信息
文献 (4)
Recent publications for all applications. Explore the full list and refine your search
Hypertension research : official journal of the Japanese Society of Hypertension 48:2218-2233 PubMed40490489
2025
Applications
Unspecified application
Species
Unspecified reactive species
Annals of translational medicine 11:4 PubMed36760249
2023
Applications
Unspecified application
Species
Unspecified reactive species
Bioengineered 12:9390-9400 PubMed34823420
2021
Applications
Unspecified application
Species
Unspecified reactive species
Oncotarget 11:3590-3600 PubMed33062195
2020
Applications
Unspecified application
Species
Unspecified reactive species
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