Anti-Ephrin A2抗体[OTI3E3]
Anti-Ephrin A2 antibody [OTI3E3]
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(4 Publications)
Mouse Monoclonal Ephrin A2 antibody. Suitable for WB, ICC/IF, Flow Cyt (Intra), IHC-P and reacts with Human, African green monkey samples. Cited in 4 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human EFNA2.
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EPLG6, LERK6, EFNA2, Ephrin-A2, EPH-related receptor tyrosine kinase ligand 6, HEK7 ligand, LERK-6, HEK7-L
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ephrin A2 antibody [OTI3E3] (AB123877)
Paraffin-embedded human endometrium tissue stained for Ephrin A2 using ab123877 at 1/100 dilution in immunohistochemical analysis.
- Flow Cyt (Intra)
Unknown
Flow Cytometry (Intracellular) - Anti-Ephrin A2 antibody [OTI3E3] (AB123877)
ab123877 at 1/100 dilution staining Ephrin-A2 in Jurkat cells by Flow Cytometry (Intracellular) (Red) compared to a nonspecific negative control antibody (Blue).
- ICC/IF
Unknown
Immunocytochemistry/ Immunofluorescence - Anti-Ephrin A2 antibody [OTI3E3] (AB123877)
COS-7 (African green monkey kidney fibroblast-like cell line) cells transiently transfected by pCMV6-ENTRY Ephrin A2, stained for Epherin A2 (Green) using ab123877 at 1/100 dilution in ICC/IF.
- WB
Unknown
Western blot - Anti-Ephrin A2 antibody [OTI3E3] (AB123877)
All lanes:
Western blot - Anti-Ephrin A2 antibody [OTI3E3] (ab123877) at 1/2000 dilution
Lane 1:
HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) cells transfected with pCMV6-ENTRY control cDNA at 5 µg
Lane 2:
HEK-293T cells transfected with pCMV6-ENTRY Ephrin A2 cDNA at 5 µg
Predicted band size: 24 kDa
false
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性能和储存信息
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存储溶液
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推荐的短期储存时间
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This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Ephrin A2 is involved in cell positioning and boundary formation. It is essential during embryonic development for tissue patterning. The ephrin A2 binds to Eph receptors often forming a complex that triggers bidirectional signaling. This complex affects neuronal growth cones guiding axon pathfinding and is significant in neurogenesis. Its signaling impacts cellular adhesion and repulsion which regulates how cells interact with their surroundings and other cells.
Pathways
Ephrin A2 is integrated into the Eph/ephrin signaling pathway which is important for various cellular responses. This signaling impacts the Rho family of GTPases which play a role in mediating cytoskeletal dynamics. Ephrin A2 also interacts with the MAPK/ERK pathway contributing to the regulation of cell proliferation and differentiation. Within these pathways it associates with proteins like EphA4 and ephrin A5 influencing pathway outcomes.
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文献 (4)
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Cancer cell international 25:191 PubMed40413506
2025
Applications
Unspecified application
Species
Unspecified reactive species
Diagnostics (Basel, Switzerland) 12: PubMed35626181
2022
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Unspecified application
Species
Unspecified reactive species
Diagnostics (Basel, Switzerland) 11: PubMed34943502
2021
Applications
Unspecified application
Species
Unspecified reactive species
Pathology international 64:415-22 PubMed25243889
2014
Applications
Unspecified application
Species
Unspecified reactive species
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