Anti-ENPP6抗体(ab127897)
Key features and details
- Rabbit polyclonal to ENPP6
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-ENPP6抗体
参阅全部 ENPP6 一抗 -
描述
兔多克隆抗体to ENPP6 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cow
-
免疫原
Recombinant fragment, corresponding to a region within amino acids 15-207 of Human ENPP6 (Q6UWR7).
-
阳性对照
- MCF7 whole cell lysate.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab127897于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 50 kDa.
|
| 说明 |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 50 kDa. |
靶标
-
相关性
ENPP6 is a choline-specific glycerophosphodiester phosphodiesterase, which hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p-nitrophenyl thymidine 5 prime-monophosphate. It hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. ENPP6 has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. ENPP6 also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently. ENPP6 is predominantly expressed in kidney and brain. -
细胞定位
Cell membrane; Single-pass type I membrane protein. Secreted. Note: A minor secreted form also exists. -
数据库链接
- Entrez Gene: 537431 Cow
- Entrez Gene: 133121 Human
- Entrez Gene: 320981 Mouse
- Entrez Gene: 306460 Rat
- SwissProt: Q58D68 Cow
- SwissProt: Q6UWR7 Human
- SwissProt: Q8BGN3 Mouse
- SwissProt: B0BND0 Rat
-
别名
- B830047L21Rik antibody
- E-NPP 6 antibody
- Ectonucleotide pyrophosphatase/phosphodiesterase 6 antibody
see all
图片
-
Western blot - Anti-ENPP6 antibody (ab127897)Anti-ENPP6 antibody (ab127897) at 1/1000 dilution + MCF7 whole cell lysate at 30 µg
Predicted band size: 50 kDa
10% SDS Page
数据表及文件
-
SDS download
-
Datasheet download
文献 (1)
ab127897 被引用在 1 文献中.
- Aranmolate A et al. Myelination is delayed during postnatal brain development in the mdx mouse model of Duchenne muscular dystrophy. BMC Neurosci 18:63 (2017). PubMed: 28806929