Anti-ENC1抗体(ab106683)
Key features and details
- Chicken polyclonal to ENC1
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgY
概述
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产品名称
Anti-ENC1抗体
参阅全部 ENC1 一抗 -
描述
鸡多克隆抗体to ENC1 -
宿主
Chicken -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse -
免疫原
Synthetic peptide corresponding to Human ENC1 (internal sequence). The immunogen is located within amino acids 230 - 280 (13 amino acid synthetic peptide) of ENC-1.
Database link: O14682 -
阳性对照
- WB: Mouse kidney muscle tissue lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
ab106683 is purified by affinity chromatography via a peptide column. -
克隆
多克隆 -
同种型
IgY -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab106683于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 66 kDa.
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| 说明 |
|---|
|
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 66 kDa. |
靶标
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功能
Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. May be down-regulated in neuroblastoma tumors. Substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. -
组织特异性
Detected in fetal brain tissue, moderate expression in fetal heart, lung and kidney. Highly expressed in adult brain, particularly high in the hippocampus and amygdala, and spinal chord. Detectable in adult pancreas. -
通路
Protein modification; protein ubiquitination. -
序列相似性
Contains 1 BTB (POZ) domain.
Contains 6 Kelch repeats. -
发展阶段
Dramatically up-regulated upon neuronal differentiation. -
翻译后修饰
Ubiquitinated and probably targeted for proteasome-independent degradation. -
细胞定位
Nucleus matrix. Cytoplasm > cytoskeleton. - Information by UniProt
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数据库链接
- Entrez Gene: 13803 Mouse
- SwissProt: O35709 Mouse
- Unigene: 241073 Mouse
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别名
- CCL 28 antibody
- CCL28 antibody
- Ectoderm neural cortex protein 1 antibody
see all
图片
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Western blot - Anti-ENC1 antibody (ab106683)All lanes : Anti-ENC1 antibody (ab106683) at 1 µg/ml
Lane 1 : Mouse Kidney muscle tissue lysate
Lane 2 : Mouse Kidney muscle tissue lysate
with blocking peptide
Lysates/proteins at 15 µg per lane.
Predicted band size: 66 kDa
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab106683 被引用在 1 文献中.
- Li X et al. Long Non-coding RNA MIAT Knockdown Prevents the Formation of Intracranial Aneurysm by Downregulating ENC1 via MYC. Front Physiol 11:572605 (2020). PubMed: 33551826