Anti-EID3抗体(ab124447)
Key features and details
- Rabbit polyclonal to EID3
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-EID3抗体 -
描述
兔多克隆抗体to EID3 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat
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免疫原
Recombinant fragment, corresponding to amino acids 139-333 of Human EID3 (BC027612).
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阳性对照
- Human fetal brain, liver, kidney lysates, HeLa, K562 and HepG2 cell lysates; fetasl testis tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Lyophilized:Reconstitute in 200ul sterile H2O. -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Preservative: 0.02% Sodium azide
Constituent: 1% BSA -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab124447于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000 - 1/2000. Predicted molecular weight: 38 kDa.
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| IHC-P |
1/100 - 1/500.
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| 说明 |
|---|
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WB
1/1000 - 1/2000. Predicted molecular weight: 38 kDa. |
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IHC-P
1/100 - 1/500. |
靶标
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功能
Act as a repressor of nuclear receptor-dependent transcription possibly by interfering with CREBBP-dependent coactivation. May function as a coinhibitor of other CREBBP/EP300-dependent transcription factors. -
组织特异性
Highly expressed in testis. -
序列相似性
Belongs to the NSE4 family. -
细胞定位
Nucleus. Cytoplasm. May shuttle between nucleus and cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 493861 Human
- Entrez Gene: 66341 Mouse
- Entrez Gene: 691688 Rat
- Omim: 612986 Human
- SwissProt: Q8N140 Human
- SwissProt: Q3V124 Mouse
- SwissProt: Q4V8G2 Rat
- Unigene: 659857 Human
see all -
别名
- E1A-like inhibitor of differentiation 3 antibody
- EID 3 antibody
- EID-1-like inhibitor of differentiation 3 antibody
see all
图片
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Western blot - Anti-EID3 antibody (ab124447)All lanes : Anti-EID3 antibody (ab124447) at 1/1000 dilution
Lane 1 : Human fetal brain lysate
Lane 2 : Human fetal liver lysate
Lane 3 : Human fetal kidney lysate
Lane 4 : HeLa cell lysate
Lane 5 : K562 cell lysate
Lane 6 : HepG2 cell lysate
Predicted band size: 38 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EID3 antibody (ab124447)ab124447 at 1/100 dilution staining EID3 in Human fetal testis tissue by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab124447 被引用在 2 文献中.
- Jia L et al. Dasatinib regulates the proliferation and osteogenic differentiation of PDLSCs through Erk and EID3 signals. Int J Med Sci 20:1460-1468 (2023). PubMed: 37790842
- Munakata K et al. Cancer Stem-like Properties in Colorectal Cancer Cells with Low Proteasome Activity. Clin Cancer Res 22:5277-5286 (2016). WB . PubMed: 27166395