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AB40815

Anti-EGFR (phospho Y1068) 抗体 [EP774Y]

Anti-EGFR (phospho Y1068) antibody [EP774Y]

  • RabMAb
  • Recombinant
  • Lab Essentials
  • 20ul selling size
  • 了解详情

4

(14 Reviews)

|

(189 Publications)

Anti-EGFR (phospho Y1068) antibody [EP774Y] (ab40815) is a rabbit monoclonal antibody detecting EGFR in Western Blot, Flow Cytometry (Intra), IHC-P, ICC/IF, Dot Blot. Suitable for Human, Mouse.

- Biophysical QC for unrivalled batch-batch consistency
- Over 140 publications
- Trusted since 2006

查看别名

ERBB, ERBB1, HER1, EGFR, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1

14 Images
Western blot - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)
  • WB

Lab

Western blot - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)

This antibody detects high background.

All lanes:

Western blot - Anti-EGFR (phospho Y1068) antibody [EP774Y] (ab40815) at 1/1000 dilution

Lane 1:

A431 (Human epidermoid carcinoma epithelial cell) whole cell lysates at 15 µg

Lane 2:

A431 (Human epidermoid carcinoma epithelial cell) treated with 10 ng/ml EGF for 30 minutes whole cell lysates at 15 µg

Lane 3:

A431 (Human epidermoid carcinoma epithelial cell) treated with 10 ng/ml EGF for 30 minutes. Then the membrane was incubated with phosphatase at 15 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/20000 dilution

Predicted band size: 134 kDa

Observed band size: 175 kDa

false

Immunocytochemistry/ Immunofluorescence - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)

Immunofluorescent staining of untreated (C) and Phosphatase- treated (D) A431 cells using ab40815 (unpurified).

Flow Cytometry (Intracellular) - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)
  • Flow Cyt (Intra)

Unknown

Flow Cytometry (Intracellular) - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)

Intracellular Flow Cytometry analysis of A431 (Human epidermoid carcinoma epithelial cell) treated with 200 ng/ml EGF for 15 minutes cells labeling EGFR with purified ab40815 at 1/800 dilution (1 μg/ml) (red). Cells were fixed with 4% Paraformaldehyde and permeabilised with 90% Methanol. A Goat anti rabbit IgG (Alexa Fluor® 488, ab150077) secondary antibody was used at 1/2000. Isotype control - Rabbit monoclonal IgG (Black). Unlabeled control - Cell without incubation with primary antibody and secondary antibody (Blue). Untreated A431 cells (Green).

Immunocytochemistry/ Immunofluorescence - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)

WD-PBEC cultures were infected with RSV clinical isolate BT2a and stained for EGFR (red) and RSV F (RSV F, green) expression.

For WD-PBECs, pediatric bronchial epithelial cells (PBEC) were obtained, via written parental consent, from bronchial brushings of children undergoing elective surgery at the Royal Belfast Hospital for Sick Children, and the procedures were approved by the Office of Research Ethics Committees Northern Ireland. PBEC were expanded in collagen-coated flasks using airway epithelial cell media and supplements (Lonza), then seeded onto transwell inserts (Corning), and then air-liquid interface (ALI) cultures were initiated and maintained 21 days in order to establish well-differentiated (WD)-PBECs. Paraformaldehyde-fixed and permeabilized WD-PBEC were stained for RSV F protein expression and were stained with anti-phospho-(p)-EGFR (Abcam, ab40815, unpurified). WD-PBEC cultures were infected with RSV subgroup A clinical isolate BT2a. Fluorescent images were obtained with a SP5 confocal DMI 6000 inverted microscope (Leica).

Immunocytochemistry/ Immunofluorescence - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)

Immunocytochemistry/ Immunofluorescence analysis of A431 (Human epidermoid carcinoma epithelial cell) treated with 100 ng/ml EGF for 10 minutes cells labeling EGFR with purified ab40815 at 1 : 500 dilution (1.8 µg/ml). Cells were fixed in 4% Paraformaldehyde and permeabilized with 0.1% tritonX-100. Cells were counterstained with ab195889 Anti-alpha Tubulin antibody [DM1A] - Microtubule Marker (Alexa Fluor® 594) at 1 : 200 (2.5 µg/ml). Goat anti rabbit IgG (Alexa Fluor® 488, ab150077) was used as the secondary antibody at 1 : 1000 (2 µg/ml) dilution. DAPI (blue) was used as nuclear counterstain. PBS instead of the primary antibody was used as the secondary antibody only control.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of Human breast cancer tissue sections labeling EGFR with purified ab40815 at 1 : 500 dilution (1.75 µg/ml). Heat mediated antigen retrieval was performed using heat mediated antigen retrieval using ab93684 (Tris/EDTA buffer, pH 9.0). ImmunoHistoProbe one step HRP Polymer (ready to use) was used as the secondary antibody. Negative control : PBS instead of the primary antibody. Hematoxylin was used as a counterstain.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)
  • IHC-P

AbReview55755****

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)

Formaldehyde-fixed, paraffin-embedded human prostate cancer tissue stained for EGFR (phospho Y1068) using ab40815 (unpurified) at 1/200 dilution in immunohistochemical analysis, followed by Goat anti Rabbit IgG (Biotin).

This image is courtesy of an anonymous Abreview.

Western blot - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)
  • WB

Lab

Western blot - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)

This antibody detects high background.

All lanes:

Western blot - Anti-EGFR (phospho Y1068) antibody [EP774Y] (ab40815) at 1/1000 dilution

Lane 1:

A431 (Human epidermoid carcinoma epithelial cell) whole cell lysates at 15 µg

Lane 2:

A431 (Human epidermoid carcinoma epithelial cell) treated with 10 ng/ml EGF for 30 minutes whole cell lysates at 15 µg

Lane 3:

A431 (Human epidermoid carcinoma epithelial cell) treated with 10 ng/ml EGF for 30 minutes. Then the membrane was incubated with phosphatase at 15 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/20000 dilution

Predicted band size: 134 kDa

Observed band size: 175 kDa

false

Western blot - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)
  • WB

Supplier Data

Western blot - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)

***Blocking and dilution buffer : *** 5% NFDM/TBST.

Lanes 1 - 3:

Western blot - Anti-EGFR (phospho Y1068) antibody [EP774Y] (ab40815) at 1/1000 dilution

Lanes 1 - 3:

Western blot - Anti-EGFR (phospho Y1068) antibody [EP774Y] - BSA and Azide free (<a href='/products/primary-antibodies/egfr-phospho-y1068-antibody-ep774y-bsa-and-azide-free-ab182618'>ab182618</a>) at 1/1000 dilution

Lane 1:

C2C12 (Mouse myoblasts myoblast) whole cell lysate at 20 µg

Lane 2:

C2C12 (Mouse myoblasts myoblast) treated with 100 ng/ml EGF for 24 hours whole cell lysate at 20 µg

Lane 3:

C2C12 (Mouse myoblasts myoblast) treated with 100 ng/ml EGF for 24hours whole cell lysate, then the membrane was incubated with phosphatase at 20 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/20000 dilution

false

Exposure time: 30s

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)

ab40815 (unpurified) showing positive staining in Glioma tissue.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)

ab40815 (unpurified) showing positive staining in Papillary carcinoma of thyroid gland tissue.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)

ab40815 (unpurified) showing positive staining in Cervical carcinoma tissue.

Dot Blot - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)
  • Dot

Unknown

Dot Blot - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)

Dot blot analysis of EGFR (pY1068) peptide (Lane 1), SMAD5 (unmodified) peptide labelling EGFR (pY1068) with ab40815 (unpurified) at a dilution of 1/1000. Peroxidase conjugated goat anti-rabbit IgG (H+L) was used as the secondary antibody at a dilution of 1/2500.

Blocking and dilution buffer : 5% NFDM/TBST.

Exposure time : 3 minutes.

OI-RD Scanning - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)
  • OI-RD Scanning

Unknown

OI-RD Scanning - Anti-EGFR (phospho Y1068) antibody [EP774Y] (AB40815)

We have systematically measured KD (the equilibrium dissociation constant between the antibody and its antigen), of more than 840 recombinant antibodies to assess not only their individual KD values but also to see the average affinity of antibody. Based on the comparison with published literature values for mouse monoclonal antibodies, Recombinant antibodies appear to be on average 1-2 order of magnitude higher affinity.

不同偶联物与剂型 (4)

  • Carrier free

    Anti-EGFR (phospho Y1068) antibody [EP774Y] - BSA and Azide free

  • 519 Alexa Fluor® 488

    Alexa Fluor® 488 Anti-EGFR (phospho Y1068) antibody [EP774Y]

  • 665 Alexa Fluor® 647

    Alexa Fluor® 647 Anti-EGFR (phospho Y1068) antibody [EP774Y]

  • 578 PE

    PE Anti-EGFR (phospho Y1068) antibody [EP774Y]

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EP774Y

亚型

IgG

不含载体蛋白

No

反应种属

Mouse, Human

应用

IHC-P, WB, Dot, Flow Cyt (Intra), ICC/IF

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

特异性

Recognises EGFR phosphorylated on Tyrosine 1068 of the mature human isoform 1 (corresponding to Y1092 from the precursor form P00533-1/p170)

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "Dot" : {"fullname" : "Dot Blot", "shortname":"Dot"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "FlowCytIntra" : {"fullname" : "Flow Cytometry (Intracellular)", "shortname":"Flow Cyt (Intra)"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "Dot-species-checked": "testedAndGuaranteed", "Dot-species-dilution-info": "1/1000", "Dot-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/5000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/250 - 1/500", "ICCIF-species-notes": "<p></p>", "FlowCytIntra-species-checked": "testedAndGuaranteed", "FlowCytIntra-species-dilution-info": "1/800", "FlowCytIntra-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/250 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol." }, "Mouse": { "Dot-species-checked": "guaranteed", "Dot-species-dilution-info": "", "Dot-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/5000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "guaranteed", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>" } } }

产品详情

Product Specifications

Anti-EGFR (phospho Y1068) antibody [EP774Y] (ab40815) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Dot Blot, Flow Cyt (Intra), ICC/IF, IHC-P, WB in human, mouse samples.
Anti-EGFR (phospho Y1068) antibody [EP774Y] (ab40815) specifically detects EGFR Phospho-Y1068 (UniProt ID: P00533; Molecular weight: 132kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL).

Quality and Validation

Abcam's high quality manufacturing and validation processes ensure Anti-EGFR (phospho Y1068) antibody [EP774Y] (ab40815) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility.
Anti-EGFR (phospho Y1068) antibody [EP774Y] (ab40815) has been cited over 140 times in peer reviewed journals and is trusted by the scientific community.
Anti-EGFR (phospho Y1068) antibody [EP774Y] (ab40815) has 12 independent reviews from customers.

Related Products
Conjugation-ready, carrier free format available for antibody clone EP774Y - ab182618.
Antibody clone EP774Y is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 488, Alexa Fluor® 647, PE (ab205827, ab205828, ab303574).

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
存储溶液
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

EGFR or Epidermal Growth Factor Receptor is a transmembrane glycoprotein that acts as a receptor for members of the epidermal growth factor family. Known alternatively as ErbB1 or HER1 this receptor has an approximate molecular weight of 170 kDa. EGFR is expressed in various cell types notably on epithelial cells and can influence multiple cellular processes through its kinase activity. It participates in the regulation of cell growth multiplication and survival by activating its kinase domain upon ligand binding.
Biological function summary

The EGFR protein plays an important role in cellular communication and signaling processes. EGFR pairs with other receptor family members to form active dimers or even higher-order complexes which in turn initiate intracellular signaling cascades. Through these complexes EGFR influences many processes including cell differentiation and repair. This function of EGFR makes it an integral part of mammalian biology affecting how cells respond to their environment by mediating changes in gene expression.

Pathways

EGFR is a central player in the MAPK and PI3K/Akt signaling pathways. Alongside other protein partners like KRAS and PI3 kinase it contributes to transmitting signals from the cell surface to the nucleus affecting gene transcription and cell behavior. These pathways are important for normal cell growth and division and aberrations in these pathways can lead to excessive or insufficient cell proliferation.

EGFR is pertinent to cancer biology including non-small cell lung cancer and glioblastoma where mutations or overexpression of the receptor frequently occur. It connects to proteins such as PTEN and BRAF which influence tumor progression and response to targeted therapies. EGFR's involvement in these disorders highlights its significance as a therapeutic target since it can be manipulated to alter disease progression.

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

靶点信息

Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed : 10805725, PubMed : 27153536, PubMed : 2790960, PubMed : 35538033). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF (PubMed : 12297049, PubMed : 15611079, PubMed : 17909029, PubMed : 20837704, PubMed : 27153536, PubMed : 2790960, PubMed : 7679104, PubMed : 8144591, PubMed : 9419975). Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules (PubMed : 27153536). May also activate the NF-kappa-B signaling cascade (PubMed : 11116146). Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling (PubMed : 11602604). Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin (PubMed : 11483589). Positively regulates cell migration via interaction with CCDC88A/GIV which retains EGFR at the cell membrane following ligand stimulation, promoting EGFR signaling which triggers cell migration (PubMed : 20462955). Plays a role in enhancing learning and memory performance (By similarity). Plays a role in mammalian pain signaling (long-lasting hypersensitivity) (By similarity).. Isoform 2 may act as an antagonist of EGF action.. (Microbial infection) Acts as a receptor for hepatitis C virus (HCV) in hepatocytes and facilitates its cell entry. Mediates HCV entry by promoting the formation of the CD81-CLDN1 receptor complexes that are essential for HCV entry and by enhancing membrane fusion of cells expressing HCV envelope glycoproteins.
See full target information EGFR phospho Y1068

文献 (189)

Recent publications for all applications. Explore the full list and refine your search

Theranostics 15:8117-8136 PubMed40860152

2025

Overactivation of EGFR signaling in skeletal stem/progenitor cells promotes bone formation and repair.

Applications

Unspecified application

Species

Unspecified reactive species

Yuxiang Hu,Yangyang Chen,Xiaoyao Peng,Haitao Li,Guosilang Zuo,Hao Xu,Fashuai Wu,Yi Wang,Zengwu Shao,Yulong Wei

Journal of experimental & clinical cancer research : CR 44:245 PubMed40830980

2025

Pyrotinib targeted EGFR/GRP78 mediated cell apoptosis in high EGFR gene copy number gastric cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Lingbo Bao,Xudong Wang,Xiuyong Liao,Dong Li,ChunXue Li,Nan Dai,Xiaoyan Dai,Jing Yang,Nana Hu,Xueling Tong,Zhenjie He,Yuancheng Zhao,Zheng Liu,Yue Hu,Jinlu Shan,Dong Wang,Mengxia Li,Qian Chen

Science advances 11:eadu2294 PubMed40680126

2025

Multiomic identification of senescent stem cell populations critical for osteoarthritis progression and therapy in subchondral bones.

Applications

Unspecified application

Species

Unspecified reactive species

Pei Lin Li,Jie Tang,Xiao Tong Li,Shi Rong Zhao,Run Xiang Xu,Zhi Dong Zhao,Zhong Li Li,Zhi Ling Li,Bo Feng Yin,Fu Hao Yu,Chu Tse Wu,Heng Zhu

Nature communications 16:6451 PubMed40651942

2025

Androgen receptor promotes arachidonic acid metabolism and angiogenic microenvironment in AFP-negative hepatocellular carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Zhilong Lin,Xiaofei Liu,Houwei Wang,Shumin Li,Ziqiang Miao,Jing Yang,Yuting Zhang,Kai Lei,Yifan Wu,Youmei Kang,Ruoyin Zheng,Zonglin Xie,Yixi Wen,Xiaoxue Ren,Chunxiao Liu,Alfred Sze-Lok Cheng,Yubin Xie,Shuling Chen,Ming Kuang,Sui Peng,Zhenwei Peng,Zihao Dai

Discover oncology 16:1196 PubMed40591172

2025

Tumor-associated macrophages derived exosomal circPLK1 promotes resistance to EGFR inhibitor osimertinib in non-small cell lung cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Chuankui Li,Xinyu Sun,Zuyi Wang

Scientific reports 15:16964 PubMed40374836

2025

Modulation of HER2 internalization enhances single-dose antibody-drug potency in HER2 gastric cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Abbey Zidel,Alex Benton,Emma Brown,Shayla Shmuel,Alex Vanover,Sandeep Surendra Panikar,Ron Bose,Haeseong Park,Andrew A Davis,Patrícia M R Pereira

Nature communications 16:3336 PubMed40199846

2025

Inhalable liposomal delivery of osimertinib and DNA for treating primary and metastasis lung cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Xianglei Fu,Yanbin Shi,Hang Wu,Yankun Zhang,Yingying Liu,Xiaoyu Wan,Xiangqin Chen,Jiamin Zhou,Shengnan Qiu,Xiaogang Zhao,Zhongxian Tian,Lian Li,Hengchang Zang,Guimei Lin

Cells 14: PubMed39791720

2025

Induction of SUSD2 by STAT3 Activation Is Associated with Tumor Recurrence in HER2-Positive Breast Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Yisun Jeong,Hyungjoo Kim,Daeun You,Soo Youn Cho,Sun Young Yoon,Seok Won Kim,Seok Jin Nam,Jeong Eon Lee,Sangmin Kim

CytoJournal 21:46 PubMed39737134

2024

Oncogene 5'-3' exoribonuclease 2 enhances epidermal growth factor receptor signaling pathway to promote epithelial-mesenchymal transition and metastasis in non-small-cell lung cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Yonghui Cheng,Mengge Wen,Xiaochun Wang,Hao Zhu

Cellular & molecular immunology 22:97-110 PubMed39653767

2024

Esophageal ILC2s mediate abnormal epithelial remodeling in eosinophilic esophagitis via Areg-EGFR signaling.

Applications

Unspecified application

Species

Unspecified reactive species

MinYeong Lim,Taesoo Kim,Hyesung Kim,Bo Gun Jang,Jae Kyung Myung,Hye Young Kim
View all publications

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