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AB167281

Anti-EGFL6抗体

Anti-EGFL6 antibody

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(1 Publication)

Mouse Polyclonal EGFL6 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human EGFL6.

查看别名

MAEG, PP648, UNQ281/PRO320, EGFL6, Epidermal growth factor-like protein 6, EGF-like protein 6, MAM and EGF domains-containing gene protein

1 Images
Western blot - Anti-EGFL6 antibody (AB167281)
  • WB

Unknown

Western blot - Anti-EGFL6 antibody (AB167281)

All lanes:

Western blot - Anti-EGFL6 antibody (ab167281) at 1 µg/mL

Lane 1:

Transfected 293T cell lysate at 15 µL

Lane 2:

Non-transfected 293T cell lysate at 15 µL

Secondary

All lanes:

Goat Anti-Mouse HRP at 1/2500 dilution

Predicted band size: 61 kDa

false

关键信息

宿主种属

Mouse

克隆

Polyclonal

亚型

IgG

不含载体蛋白

No

反应种属

Human

应用

WB

applications

免疫原

Recombinant Full Length Protein corresponding to Human EGFL6.

Q8IUX8

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>" } } }
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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
存储溶液
pH: 7.4 Constituents: PBS
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

EGFL6 also known as Epidermal Growth Factor-Like Protein 6 or MAEG is a secreted protein that plays a role in the regulation of cell growth. It belongs to the epidermal growth factor (EGF) repeat superfamily and has an approximate mass of 70 kDa. EGFL6 is expressed in various tissues with higher expression noted in fetal tissues particularly the lung and kidney as well as in certain adult tissues like the ovary.
Biological function summary

This protein influences cell proliferation and differentiation. EGFL6 is not a part of a larger protein complex but functions through its interactions with other cellular components. Its activity affects cell behavior which is especially noted during development and tissue regeneration processes. EGFL6 modulates the extracellular environment through binding to receptor tyrosine kinases mediating signaling that promotes cellular motility and survival.

Pathways

EGFL6 integrates into significant pathways such as the PI3K/AKT and MAPK signaling pathways. Through these pathways it maintains cellular processes related to growth and survival by interacting with proteins like AKT1 and MAPK1. These signaling cascades are fundamental in mediating responses to growth factors and adjusting cell fate decisions.

Aberrant expression of EGFL6 associates with conditions such as cancer specifically ovarian cancer and melanoma. In these contexts EGFL6 interplays with proteins like VEGF contributing to tumor growth and angiogenesis. Its role in disease suggests potential as a therapeutic target for interventions designed to modulate cancer progression.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly (By similarity).
See full target information EGFL6
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

BMC cancer 23:96 PubMed36707804

2023

Histone methyltransferase SETD1A interacts with notch and promotes notch transactivation to augment ovarian cancer development.

Applications

Unspecified application

Species

Unspecified reactive species

Hongjuan Chai,Chunpeng Pan,Mingyang Zhang,Haizhong Huo,Haiyan Shan,Jugang Wu
View all publications
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替代产品

Primary Antibodies

AB140079

Anti-EGFL6 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EGFL6 antibody (AB140079)

  • 0
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搭配使用产品

Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

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Primary Antibodies

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Primary Antibodies

AB2796

Anti-NFAT2 antibody [7A6]

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Primary Antibodies

AB81283

Anti-AKT1 (phospho S473) antibody [EP2109Y]

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