Anti-EG-VEGF抗体[MM0043-2L13] (ab72807)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EG-VEGF antibody [MM0043-2L13] (ab72807)](https://www.abcam.cn/ps/products/72/ab72807/Images/ab72807-88053-anti-eg-vegf-antibody-mm0043-2l13-immunohistochemistry.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EG-VEGF antibody [MM0043-2L13] (ab72807)")
Key features and details
- Mouse monoclonal [MM0043-2L13] to EG-VEGF
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG2
概述
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产品名称
Anti-EG-VEGF抗体[MM0043-2L13]
参阅全部 EG-VEGF 一抗 -
描述
小鼠单克隆抗体[MM0043-2L13] to EG-VEGF -
宿主
Mouse -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length protein corresponding to Human EG-VEGF.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Constituent: PBS -
Concentration information loading... -
纯度
Protein G purified -
克隆
单克隆 -
克隆编号
MM0043-2L13 -
同种型
IgG2 -
研究领域
相关产品
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Compatible Secondaries
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab72807于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/50 - 1/100.
|
| 说明 |
|---|
|
IHC-P
1/50 - 1/100. |
靶标
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功能
Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis. -
组织特异性
Localizes to glandular epithelium, stroma and vascular epithelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the steroidogenic glands, ovary, testis, adrenal and placenta. -
序列相似性
Belongs to the AVIT (prokineticin) family. -
发展阶段
In adult testis, is strongly expressed only in Leydig cells. In testicular tumors, expressed specifically in Leydig cell tumors (at protein level). Expressed from 14 weeks until birth in fetal testis. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 84432 Human
- Omim: 606233 Human
- SwissProt: P58294 Human
- Unigene: 514793 Human
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别名
- Black mamba toxin related protein antibody
- EG VEGF antibody
- EG-VEGF antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EG-VEGF antibody [MM0043-2L13] (ab72807)
ab72807 at 1/100 dilution, staining EG-VEGF in human placenta tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections).
数据表及文件
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Datasheet download
文献 (6)
ab72807 被引用在 6 文献中.
- Wang Y et al. miR-181a, delivered by hypoxic PTC-secreted exosomes, inhibits DACT2 by downregulating MLL3, leading to YAP-VEGF-mediated angiogenesis. Mol Ther Nucleic Acids 24:610-621 (2021). PubMed: 33898109
- Wang Y & Jiang L Role of vitamin D-vitamin D receptor signaling on hyperoxia-induced bronchopulmonary dysplasia in neonatal rats. Pediatr Pulmonol 56:2335-2344 (2021). PubMed: 33878208
- Zhan C et al. Effect of the Notch4/Dll4 signaling pathway in early gestational intrauterine infection on lung development. Exp Ther Med 22:972 (2021). PubMed: 34335914
- Sheng H et al. Combined Pharmacotherapy with Alendronate and Desferoxamine Regulate the Bone Resorption and Bone Regeneration for Preventing Glucocorticoids-Induced Osteonecrosis of the Femoral Head. Biomed Res Int 2020:3120458 (2020). PubMed: 33029500
- Zheng Y et al. Silencing of Long Non-Coding RNA LINC00607 Prevents Tumor Proliferation of Osteosarcoma by Acting as a Sponge of miR-607 to Downregulate E2F6. Front Oncol 10:584452 (2020). PubMed: 33585204
- Meng L et al. miR-28-5p suppresses cell proliferation and weakens the progression of polycystic ovary syndrome by targeting prokineticin-1. Mol Med Rep 20:2468-2475 (2019). PubMed: 31322191
