Anti-EB3 (phospho S162)抗体[KT113] (ab179877)
Key features and details
- Mouse monoclonal [KT113] to EB3 (phospho S162)
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG1
概述
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产品名称
Anti-EB3 (phospho S162)抗体[KT113]
参阅全部 EB3 一抗 -
描述
小鼠单克隆抗体[KT113] to EB3 (phospho S162) -
宿主
Mouse -
特异性
ab179877 does not cross-react with EB3 if not phosphorylated at S162. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human EB3 (phospho S162). Conjugated to carrier protein.
Database link: Q9UPY8 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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纯度
Protein A purified -
纯化说明
Purified from culture supernatant. -
克隆
单克隆 -
克隆编号
KT113 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab179877于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/1000 - 1/20000. Predicted molecular weight: 31 kDa.
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说明 |
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WB
1/1000 - 1/20000. Predicted molecular weight: 31 kDa. |
靶标
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功能
May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration. -
组织特异性
Predominantly expressed in brain and muscle. -
序列相似性
Belongs to the MAPRE family.
Contains 1 CH (calponin-homology) domain.
Contains 1 EB1 C-terminal domain. -
结构域
Composed of two functionally independent domains. The N-terminal domain forms an hydrophobic cleft involved in microtubule binding and the C-terminal is involved in the formation of mutually exclusive complexes with APC and DCTN1. -
细胞定位
Cytoplasm > cytoskeleton. Associated with the microtubule network. - Information by UniProt
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数据库链接
- Entrez Gene: 22924 Human
- Omim: 605788 Human
- SwissProt: Q9UPY8 Human
- Unigene: 515860 Human
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别名
- APC binding protein antibody
- EB 3 antibody
- EB1 protein family member 3 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab179877 尚未被引用在任何文献中。