Anti-E2F5抗体(ab44996)
Key features and details
- Rabbit polyclonal to E2F5
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
概述
-
产品名称
Anti-E2F5抗体
参阅全部 E2F5 一抗 -
描述
兔多克隆抗体to E2F5 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse, Rat, Human -
免疫原
Synthetic peptide corresponding to Human E2F5 aa 1-50 (N terminal). 50 amino acid range mapping within amino acids 1-50 ESF-5
-
阳性对照
- MCF7, NIH/3T3 cells.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.1% Sodium azide
Constituent: 0.01% PBS -
Concentration information loading...
-
纯度
Protein G purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab44996于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
Use at an assay dependent concentration.
|
说明 |
---|
WB
Use at an assay dependent concentration. |
靶标
-
功能
Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation. -
序列相似性
Belongs to the E2F/DP family. -
细胞定位
Nucleus. - Information by UniProt
-
数据库链接
- Entrez Gene: 1875 Human
- Entrez Gene: 13559 Mouse
- Entrez Gene: 116651 Rat
- Omim: 600967 Human
- SwissProt: Q15329 Human
- SwissProt: Q61502 Mouse
- SwissProt: Q62814 Rat
- Unigene: 445758 Human
see all -
别名
- E2F 5 antibody
- E2F transcription factor 5 antibody
- E2F transcription factor 5 p130 binding antibody
see all
数据表及文件
-
SDS download
-
Datasheet download
文献 (3)
ab44996 被引用在 3 文献中.
- Sun F et al. MicroRNA-544 inhibits esophageal squamous cell carcinoma cell proliferation and enhances sensitivity to cisplatin by repressing E2F transcription factor 5. Oncol Lett 18:4203-4209 (2019). PubMed: 31579422
- Li SM et al. The putative tumour suppressor miR-1-3p modulates prostate cancer cell aggressiveness by repressing E2F5 and PFTK1. J Exp Clin Cancer Res 37:219 (2018). PubMed: 30185212
- Vuong L et al. Pattern of expression of p53, its family members, and regulators during early ocular development and in the post-mitotic retina. Invest Ophthalmol Vis Sci 53:4821-31 (2012). PubMed: 22714890