Anti-Dynamin 1 (phospho S774)抗体(ab55324)
Key features and details
- Rabbit polyclonal to Dynamin 1 (phospho S774)
- Suitable for: ELISA, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
概述
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产品名称
Anti-Dynamin 1 (phospho S774)抗体
参阅全部 Dynamin 1 一抗 -
描述
兔多克隆抗体to Dynamin 1 (phospho S774) -
宿主
Rabbit -
经测试应用
适用于: ELISA, WBmore details -
种属反应性
与反应: Mouse, Rat, Human -
免疫原
Synthetic peptide corresponding to Human Dynamin 1 aa 700-800 (phospho S774).
Database link: Q05193 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab55324于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ELISA |
Use at an assay dependent concentration.
|
|
| WB | (1) |
1/500 - 1/1000. Detects a band of approximately 98 kDa (predicted molecular weight: 98 kDa).
|
| 说明 |
|---|
|
ELISA
Use at an assay dependent concentration. |
|
WB
1/500 - 1/1000. Detects a band of approximately 98 kDa (predicted molecular weight: 98 kDa). |
靶标
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功能
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis. -
序列相似性
Belongs to the dynamin family.
Contains 1 GED domain.
Contains 1 PH domain. -
细胞定位
Cytoplasm. Cytoplasm > cytoskeleton. Microtubule-associated. - Information by UniProt
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数据库链接
- Entrez Gene: 1759 Human
- Entrez Gene: 13429 Mouse
- Entrez Gene: 140694 Rat
- Omim: 602377 Human
- SwissProt: Q05193 Human
- SwissProt: P39053 Mouse
- SwissProt: P21575 Rat
- Unigene: 522413 Human
see all -
别名
- B dynamin antibody
- D100 antibody
- DNM 1 antibody
see all
图片
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Western blot - Anti-Dynamin 1 (phospho S774) antibody (ab55324)All lanes : Anti-Dynamin 1 (phospho S774) antibody (ab55324) at 1/500 dilution
Lane 1 : Mouse brain extract
Lane 2 : Mouse brain extract treated with the immunising phosphopeptide.
Predicted band size: 98 kDa
Observed band size: 98 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (6)
ab55324 被引用在 6 文献中.
- Du JJ et al. Clathrin-independent but dynamin-dependent mechanisms mediate Ca2+-triggered endocytosis of the glutamate GluK2 receptor upon excitotoxicity. J Integr Neurosci 19:449-458 (2020). PubMed: 33070524
- Priya R et al. Activity Regulates Cell Death within Cortical Interneurons through a Calcineurin-Dependent Mechanism. Cell Rep 22:1695-1709 (2018). WB ; Mouse . PubMed: 29444424
- Chen PH et al. Crosstalk between CLCb/Dyn1-Mediated Adaptive Clathrin-Mediated Endocytosis and Epidermal Growth Factor Receptor Signaling Increases Metastasis. Dev Cell 40:278-288.e5 (2017). PubMed: 28171750
- Reis CR et al. Crosstalk between Akt/GSK3ß signaling and dynamin-1 regulates clathrin-mediated endocytosis. EMBO J 34:2132-46 (2015). PubMed: 26139537
- Mori H et al. Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin ß1. Development 140:343-52 (2013). WB ; Mouse . PubMed: 23250208
- Martins-de-Souza D et al. Phosphoproteomic differences in major depressive disorder postmortem brains indicate effects on synaptic function. Eur Arch Psychiatry Clin Neurosci 262:657-66 (2012). WB ; Human . PubMed: 22350622