Anti-DUOX1抗体(ab78919)
Key features and details
- Goat polyclonal to DUOX1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-DUOX1抗体
参阅全部 DUOX1 一抗 -
描述
山羊多克隆抗体to DUOX1 -
宿主
Goat -
特异性
This antibody is expected to recognise both reported isoforms (NP_059130.2 ; NP_787954.1) which are identical. -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human DUOX1 aa 1020-1032 (internal sequence). Synthetic peptide:
EKFQRSCLHQTVQ
, corresponding to internal sequence amino acids 1020-1032 of Human DUOX1 (NP_059130.2 ; NP_787954.1)
Sequence:EKFQRSCLHQTVQ
Database link: Q9NRD9 -
阳性对照
- Human placenta and thyroid gland lysates.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab78919于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
Use a concentration of 4 - 6 µg/ml.
|
| 说明 |
|---|
|
IHC-P
Use a concentration of 4 - 6 µg/ml. |
靶标
-
相关性
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene (from EntrezGene). -
细胞定位
Cell Membrane -
数据库链接
- Entrez Gene: 53905 Human
- Omim: 606758 Human
- SwissProt: Q9NRD9 Human
-
别名
- Dual oxidase 1 antibody
- Dual oxidase 1 precursor antibody
- DUOX1 antibody
see all
图片
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DUOX1 antibody (ab78919)
Immunohistochemical analysis of paraffin embedded Human thyroid gland labeling DUOX1 with ab78919 at 4-6μg/ml. The image shows staining of membranes in epithelial cells of the thyroid gland.
Steamed antigen retrieval with Tris/EDTA buffer pH 9 was performed. Antibody was detected by HRP-staining.
数据表及文件
-
Datasheet download
文献 (1)
ab78919 被引用在 1 文献中.
- Yang N et al. LincRNA-p21 activates endoplasmic reticulum stress and inhibits hepatocellular carcinoma. Oncotarget 6:28151-63 (2015). WB . PubMed: 26305675
