Key features and details
- Dual color: FITC + PE Mouse monoclonal [EDU-2 + 733] to CD4 + CD8
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: Dual color: FITC + PE
产品名称Dual color: FITC荧光+ PE Anti-CD4 + CD8抗体[EDU-2 + 733]
参阅全部 CD4 + CD8 一抗
描述Dual color: FITC荧光+ PE小鼠单克隆抗体[EDU-2 + 733] to CD4 + CD8
偶联物Dual color: FITC + PE
经测试应用适用于: Flow Cytmore details
Tissue, cells or virus. Stimulated human leukocytes
This cocktail is mix of: CD4 = Clone:EDU-2, Isotype:IgG2a, Labeled with FITC and CD8 = Clone:733, Isotype:IgG1, Labeled with PE.This product contains sodium azide, which under acid conditions yields hydrazoic acid, a toxic compound. Azide compounds should be diluted with running water before being discarded to avoid deposits in lead or copper plumbing where explosive conditions may develop.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Please note that this antibody is an oligoclonal antibody. It is a cocktail of monoclonal antibodies that have been carefully selected. Oligoclonal antibodies have not only the specificity and batch-to-batch consistency of a monoclonal antibody, but also have the advantage of the sensitivity of a polyclonal antibody due to their ability to recognize multiple epitopes on an antigen.
存放说明Shipped at 4°C. Store at +4°C.
存储溶液Preservative: 0.1% Sodium azide
Constituent: 0.5% BSA
Concentration information loading...
克隆编号EDU-2 + 733
The Abpromise guarantee
Percentage count of T suppressor/cytotoxic lymphocytes (CD8+).
Control autoimmune pathologies, immunodeficiencies and immunosuppressivetherapies.
Studies of HIV (Human Immunodeficiency Virus) infection.
CD4(FITC) / CD8 (PE) immunofluorescence analysis can be performed on a flow cytometerequipped with an excitation source of 488nm and fitted with logarithmic amplifiers.
10µl ofCD4(FITC) / CD8 (PE) is sufficient for labelling 1x106 cells.
相关性CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
细胞定位Membrane; single pass type I membrane protein.
- CD4 antigen antibody
- CD4 molecule antibody
- CD4 mut antibody
ab1232 被引用在 1 文献中.
- Wang D et al. Genome-wide DNA methylation pattern in a mouse model reveals two novel genes associated with Staphylococcus aureus mastitis. Asian-Australas J Anim Sci 33:203-211 (2020). PubMed: 31010979