Anti-Draxin抗体(ab119707)
Key features and details
- Rabbit polyclonal to Draxin
- Suitable for: WB, ICC
- Reacts with: Mouse, Rat, Chicken
- Isotype: IgG
概述
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产品名称
Anti-Draxin抗体
参阅全部 Draxin 一抗 -
描述
兔多克隆抗体to Draxin -
宿主
Rabbit -
经测试应用
适用于: WB, ICCmore details -
种属反应性
与反应: Mouse, Rat, Chicken
预测可用于: Human
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免疫原
Synthetic peptide corresponding to Human Draxin (C terminal) conjugated to keyhole limpet haemocyanin.
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阳性对照
- Rat PC12 cells and cell lysate; Rat P1 brain, chick E9 brain and adult Mouse brain lysates.
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常规说明
Do not aliquot.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.1% BSA -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
ab119707 was peptide affinity purified. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab119707于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 38 kDa).
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| ICC |
1/100.
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| 说明 |
|---|
|
WB
1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 38 kDa). |
|
ICC
1/100. |
靶标
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功能
Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. -
序列相似性
Belongs to the draxin family. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 419492 Chicken
- Entrez Gene: 374946 Human
- Entrez Gene: 70433 Mouse
- Entrez Gene: 691317 Rat
- Omim: 612682 Human
- SwissProt: Q8NBI3 Human
- SwissProt: Q6PAL1 Mouse
- Unigene: 632364 Human
see all -
别名
- AGPA3119 antibody
- Chromosome 1 open reading frame 187 antibody
- Dorsal inhibitory axon guidance protein antibody
see all
图片
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Western blot - Anti-Draxin antibody (ab119707)All lanes : Anti-Draxin antibody (ab119707) at 1/1000 dilution
Lane 1 : Rat PC12 cell lysate
Lane 2 : Rat P1 brain lysate
Lane 3 : Adult mouse brain lysate
Lane 4 : Chick E9 brain lysate
Predicted band size: 38 kDa -
Immunocytochemistry - Anti-Draxin antibody (ab119707)ab119707 at 1/100 dilution staining Draxin in Rat PC12 cells, differentiated with NGF, by Immunocytochemistry in the absence (left) or presence (right) of blocking peptide. The lower images show corresponding phase images.
detection used an appropriate secondary antibody conjugated to Cy3.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab119707 尚未被引用在任何文献中。