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AB23701

Anti-DPL抗体

Anti-DPL antibody

1

(2 Reviews)

|

(1 Publication)

Rabbit Polyclonal DPL antibody. Suitable for WB and reacts with Mouse samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human PRND aa 100-150.

查看别名

DPL, UNQ1830/PRO3443, PRND, Prion-like protein doppel, PrPLP, Prion protein 2

1 Images
Western blot - Anti-DPL antibody (AB23701)
  • WB

Unknown

Western blot - Anti-DPL antibody (AB23701)

All lanes:

Western blot - Anti-DPL antibody (ab23701) at 2 µg/mL

Lane 1:

27ug mouse spleen 100k x g supernatant.

Lane 2:

54ug mouse spleen 100k x g supernatant.

Predicted band size: 20 kDa

Observed band size: 19 kDa,25 kDa

false

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

No

反应种属

Mouse

应用

WB

applications

免疫原

Synthetic Peptide within Human PRND aa 100-150. The exact immunogen used to generate this antibody is proprietary information.

Q9UKY0

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搭配使用产品

Primary Antibodies

AB7291

Anti-alpha Tubulin antibody [DM1A] - Loading Control

BOND RX™ Validated

Western blot - Anti-alpha Tubulin antibody [DM1A] - Loading Control (AB7291)

  • 5
  • 92
Proteins & Peptides

AB276638

Recombinant Human DPL protein (His tag)

SDS-PAGE - Recombinant Human DPL protein (His tag) (AB276638)

  • 0
  • 0
Primary Antibodies

AB179467

Anti-Actin antibody [EPR16769] - Loading Control

20ul selling size|RabMAb|Recombinant|Lab Essentials

Flow Cytometry (Intracellular) - Anti-Actin antibody [EPR16769] - Loading Control (AB179467)

  • 5
  • 11
Assay Kits

AB206386

TUNEL Assay Kit - HRP-DAB

Immunohistochemistry - TUNEL Assay Kit - HRP-DAB (AB206386)

  • 4
  • 3
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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "2 µg/mL", "WB-species-notes": "<p></p>" } } }
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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Immunogen
存储溶液
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: Tris buffered saline, 50% Glycerol (glycerin, glycerine), 0.1% BSA
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

The term DPL often refers to a protein involved in cellular processes and may also be known as "dpl" or "aa dpl". Its exact molecular mass can vary based on the isoform and the species in which it is found. DPL is expressed in various tissues including the brain liver and heart making it an important target for therapeutic studies in diverse physiological contexts. Researchers investigate this protein to understand better its mechanical roles in maintaining cellular functions.
Biological function summary

DPL participates in cellular signaling and structural integrity. It sometimes acts as part of a larger protein complex facilitating communication and interactions between cells. The molecular interactions with other proteins help maintain cellular homeostasis. The coupling with other cellular components might also contribute to energy metabolism and cytoskeletal organization critical to cell health and function.

Pathways

DPL plays a role in specific signaling pathways like the MAPK/ERK and PI3K/AKT pathways. These pathways are significant for cell proliferation differentiation and survival. DPL interacts with other proteins such as Raf and PI3K enabling these signaling cascades essential for cellular responses to external stimuli. The pathways involving DPL are important for understanding various cellular mechanisms and how they relate to broader biological activities across systems.

DPL has connections to certain conditions including cancer and cardiovascular diseases. Abnormal expression or mutations in DPL can disrupt normal cellular signaling contributing to tumorigenesis and heart dysfunction. In cancer DPL may interact with oncogenes like KRAS affecting tumor growth and spread. In heart disorders alterations in DPL-associated pathways could impact cardiac cell function connecting it to other proteins such as troponin related to heart muscle contraction abnormalities.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Required for normal acrosome reaction and for normal male fertility (By similarity). Can bind Cu(2+) (PubMed : 15218028, PubMed : 20411530).
See full target information PRND
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Cells 13: PubMed38995003

2024

Hypoxia Promotes Invadosome Formation by Lung Fibroblasts.

Applications

Unspecified application

Species

Unspecified reactive species

Mégane Lebel,Dominic O Cliche,Martine Charbonneau,Karine Brochu-Gaudreau,Damien Adam,Emmanuelle Brochiero,Claire M Dubois,André M Cantin
View all publications
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