AB126080

Anti-Dkk3 抗体

Anti-Dkk3 antibody

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(5 Publications)

Rabbit Polyclonal Dkk3 antibody. Suitable for WB and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Recombinant Fragment Protein within Human DKK3 aa 50 to C-terminus.

查看别名

REIC, UNQ258/PRO295, DKK3, Dickkopf-related protein 3, Dickkopf-3, Dkk-3, hDkk-3

1 Images

Unknown

Western blot - Anti-Dkk3 antibody (AB126080)

Gel concentration : 10%

All lanes:

Western blot - Anti-Dkk3 antibody (ab126080) at 1/1000 dilution

All lanes:

293T whole cell lysate at 30 µg

Predicted band size: 38 kDa

false

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

反应种属

Human

应用

applications

免疫原

Recombinant Fragment Protein within Human DKK3 aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q9UBP4

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" } } }

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Immunogen

存储溶液

pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 20% Glycerol (glycerin, glycerine), 1% BSA

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

See full target information DKK3

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文献 (5)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in oncology 12:948023 PubMed35924156

2022

Apogossypolone Inhibits Cell Proliferation and Epithelial-Mesenchymal Transition in Cervical Cancer Activating DKK3.

Applications

Unspecified application

Species

Unspecified reactive species

Yuling Li,Jinfeng Qu,Lu Liu,Yu Sun,Junhua Zhang,Sai Han,Youzhong Zhang

European journal of medical research 26:93 PubMed34391478

2021

Dickkopf-related protein 3 alters aerobic glycolysis in pancreatic cancer BxPC-3 cells, promoting CD4 T-cell activation and function.

Applications

Unspecified application

Species

Unspecified reactive species

Qingqu Guo,Yiming Chu,Hongbo Li,Dike Shi,Lele Lin,Weifeng Lan,Dan Wu

Cells 10: PubMed33670899

2021

Integrated Proteomic and Phosphoproteomics Analysis of DKK3 Signaling Reveals Activated Kinase in the Most Aggressive Gallbladder Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Kirti Gondkar,Gajanan Sathe,Neha Joshi,Bipin Nair,Akhilesh Pandey,Prashant Kumar

Frontiers in oncology 9:1121 PubMed31737564

2019

Dickkopf Homolog 3 Acts as a Potential Tumor Suppressor in Gallbladder Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Kirti Gondkar,Krishna Patel,Geeta V Patil Okaly,Bipin Nair,Akhilesh Pandey,Harsha Gowda,Prashant Kumar

Oncogene 34:1520-31 PubMed24727892

2014

CD58, a novel surface marker, promotes self-renewal of tumor-initiating cells in colorectal cancer.

Applications

Unspecified application

Species

Unspecified reactive species

S Xu,Z Wen,Q Jiang,L Zhu,S Feng,Y Zhao,J Wu,Q Dong,J Mao,Y Zhu

View all publications

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Anti-Dkk3 抗体

Anti-Dkk3 antibody

Western blot - Anti-Dkk3 antibody (AB126080)

关键信息

宿主种属

克隆

亚型

不含载体蛋白

反应种属

应用

免疫原

反应性数据

性能和储存信息

形式

纯化工艺

存储溶液

运输条件

推荐的长期储存条件

分装信息

储存信息

产品实验方案

靶点信息

文献 (5)

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