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AB201080

Anti-DDX24抗体

Anti-DDX24 antibody

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(1 Publication)

Rabbit Polyclonal DDX24 antibody. Suitable for WB and reacts with Human, Mouse, Rat samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human DDX24 aa 50-150.

查看别名

ATP-dependent RNA helicase DDX24, DEAD box protein 24, DDX24

1 Images
Western blot - Anti-DDX24 antibody (AB201080)
  • WB

Supplier Data

Western blot - Anti-DDX24 antibody (AB201080)

All lanes:

Western blot - Anti-DDX24 antibody (ab201080)

Lane 1:

A549 whole cell lysate

Lane 2:

PC12 whole cell lysate

Lane 3:

sp20 whole cell lysate

Predicted band size: 96 kDa

false

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

No

反应种属

Mouse, Rat, Human

应用

WB

applications

免疫原

Synthetic Peptide within Human DDX24 aa 50-150. The exact immunogen used to generate this antibody is proprietary information.

Q9GZR7

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "<p></p>" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Immunogen
存储溶液
pH: 7.3 Preservative: 0.05% Sodium azide Constituents: PBS
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

DDX24 also known as DEAD-box helicase 24 is a member of the DEAD box protein family and functions as an ATP-dependent RNA helicase. This protein has a molecular mass of approximately 91 kDa. It is expressed in various tissues with notable levels seen in testis and heart. The expression pattern indicates its involvement in cellular processes that require tight regulation of RNA metabolism.
Biological function summary

DEAD-box helicases like DDX24 are important in RNA processing and ribosome biogenesis. DDX24 contributes to pre-rRNA processing by participating in the production and assembly of ribosomal subunits. The protein is also a part of the ribonucleoprotein complex where it influences the regulation of RNA interference processes. This suggests its essential role in RNA stability and gene expression regulation.

Pathways

DDX24 plays a significant role in the ribosome biogenesis pathway and RNA processing pathways. Both are fundamental for efficient protein synthesis. Within these pathways DDX24 interacts with other proteins like NOP56 and fibrillarin which are influential in the process of rRNA modification and folding. Such interactions are vital for the proper assembly of ribosomal subunits and their correct function in protein translation.

Dysregulation of DDX24 expression or function has been linked to certain cancers such as brain tumors where alterations in RNA processing are frequent. Moreover irregular DDX24 activity has been associated with viral infections such as HIV where the virus exploits host RNA processing machineries. This connection includes proteins like DDX6 which work with DDX24 during the viral replication cycle affecting the host's cellular environment and promoting disease progression.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

ATP-dependent RNA helicase.
See full target information DDX24
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

EMBO reports 26:218-244 PubMed39609640

2024

The TGF-β mimic TGM4 achieves cell specificity through combinatorial surface co-receptor binding.

Applications

Unspecified application

Species

Unspecified reactive species

Shashi P Singh,Danielle J Smyth,Kyle T Cunningham,Ananya Mukundan,Chang-Hyeock Byeon,Cynthia S Hinck,Madeleine P J White,Claire Ciancia,Natalia Wąsowska,Anna Sanders,Regina Jin,Ruby F White,Sergio Lilla,Sara Zanivan,Christina Schoenherr,Gareth J Inman,Maarten van Dinther,Peter Ten Dijke,Andrew P Hinck,Rick M Maizels
View all publications
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